Cardiology Medical News about left ventricular volumes;3D echocardiographic speckle tracking

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Quantification of left ventricular volumes using three-dimensional echocardiographic speckle tracking: comparison with MRI
European Heart Journal, 06/04/09

Nesser HJ et al. – Findings are the first to validate the new three-dimensional (3D)-speckle tracking echocardiography (STE) technique for left ventricular (LV) volume measurements and to show its superior accuracy and reproducibility over the previously used two-dimensional (2D)-STE technique.

Methods

Study of the accuracy of the new 3D-STE side-by-side with 2D-STE using cardiac magnetic resonance (CMR) as a reference
Evaluation of apical 2- and 4-chamber views (A2C and A4C) and real-time 3D datasets in 43 pts with a wide range of LV size and function
Measurement of LV end-systolic and end-diastolic volumes (ESV and EDV) by 2D and 3D-STE techniques
Analysis of same-day, short-axis CMR images for ESV and EDV reference values by disks approximation method
Repeat measurement to assess reproducibility of both STE techniques

Results

2D-STE correlated well with CMR but underestimated LV volumes with relatively large biases (10–30 mL) and wide limits of agreement (SD: 36–51 mL)
A2C-derived measurements worse than A4C values
3D-STE measurements showed higher correlation with CMR (0.87–0.92) and smaller biases (1–16 mL) and narrower limits of agreement (SD: 28–37 mL)
3D-STE showed lower inter- and intra-observer variability (11–14% and 12–13%), than 2D-STE (16–17% and 12–16%, respectively)

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