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Complement activation by carotenoid derived aldehydes in cultured human vein epithelial cells
Phytotherapy Research, 05/18/09
Wu P-L et al. - This study was designed to determine the complement activation effects of carotenoid-derived aldehydes (CDA) on cultured human umbilical vein endothelial cells (HUVEC). A dose-dependent complement activation upon incubation of HUVEC with CDA was observed. Interestingly, the data showed that the alternative pathway was not activated. In addition, upon CDA treatment a significant number of apoptotic cells was also observed. The results revealed that CDA could activate the complement by way of the classical pathway. The study suggests that high carotenoid supplementation for the treatment of coronary heart disease should be used cautiously.
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A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial
The Lancet, 10/27/09
Obesity-Related Cardiorenal Syndrome
The Journal of Clinical Hypertension, 10/20/09
Inflammatory mediators and premature coronary atherosclerosis in rheumatoid arthritis
Arthritis Care and Research , 11/03/09
Today in Complementary Medicine...keeping you current
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Omega-3 Augmentation of Sertraline in Treatment of Depression in Patients With Coronary Heart Disease: A Randomized Controlled Trial
JAMA, 10/22/09
Oral Magnesium Supplementation Reduces Ambulatory Blood Pressure in Patients With Mild Hypertension
American Journal of Hypertension, 09/25/09
Coenzyme Q10 improves diastolic function in children with idiopathic dilated cardiomyopathy
Cardiology in the Young, 10/19/09
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