Cardiology Medical News about Heart Transplantation

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. Pre-participation screening of young competitive athletes for prevention of sudden cardiac death

3. The Job Market for 2008-2009: Compensation

4. Renal Artery Stenosis

5. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Asymptomatic Antibody-mediated Rejection After Heart Transplantation Predicts Poor Outcomes
The Journal of Heart and Lung Transplantation, 05/12/09

Wu GW et al. - Despite comparable 5-year survival with controls after heart transplantation, AsAMR rejection is associated with a greater risk of CAV. Trials to treat AsAMR to alter outcome are warranted.

Exclusive Author Commentary
Jon A. Kobashigawa , 05/12/09

This is the first paper to assess the significance of antibody mediated rejection without symptoms having poor outcome in heart transplant patients. This paper implicates antibody mediated rejection in the pathogenesis of cardiac allograft vasculopathy, a major cause of long-term mortality in this patient population. The evidence presented suggests that either preventive therapy for antibody mediated rejection or preemptive therapy once asymptomatic antibody mediate rejection has been found on heart biopsy, could possibly alter outcomes. This manuscript warrants future studies to assess therapies and outcomes of heart transplant patients with asymptomatic antibody mediated rejection.

<< Previous
Assessment of Arterial Blood Pressure During Support With an...

Next >>
Chronic Kidney Disease is Associated With Decreased Exercise...