Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Pre-participation screening of young competitive athletes for prevention of sudden cardiac death 3. The Job Market for 2008-2009: Compensation 4. Renal Artery Stenosis 5. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease
Your Article Summary
See Latest ArticlesPotential impact of omega-3 treatment on cardiovascular disease in type 2 diabetes
Current Opinion in Lipidology, 01/09/09
Hartweg J et al. – A systematic review and meta-analysis confirms triglyceride lowering effects of omega-3 polyunsaturated fatty acids (PUFAs) and shows potential dose-response effects and improvements in thrombogenesis. Omega-3 PUFAs raise LDL levels without concomitant changes in lipid particle size. Changes in conventional risk factors are insufficient to explain the cardiovascular disease risk reductions proposed with omega-3 PUFAs.
Methods- Hypothesis-generating systematic review of the impact of marine-derived omega-3 PUFAs on lipid, glycemic, and hematologic risk factors in type 2 diabetes
- Review of pooled data from randomized controlled trials to 20 September 2008
- Pooled data: 7 new trials in 2007/2008 from 206 abstracts for total of 24 trials 1966-2008 of 1533 subjects
- Mean omega-3 PUFAs treatment dose and duration in new trials: 2.4 g/day for 24 wks
- Compared with placebo, omega-3 PUFAs supplementation decreased triglycerides by 7%, fibrinogen by 10%, ADP platelet aggregation to ADP by 22%, and to collagen by 21%, with an LDL-cholesterol increase of 3%
- None of following risk factors appeared beneficially influenced: HDL-cholesterol, LDL particle size, glycemia, insulinemia, inflammatory biomarkers, blood pressure
- Few trial pts for some risk factors (such as inflammtory biomarkers)
- Higher doses of omega-3 PUFAs (≥2 g/day) may have greater triglyceride-lowering effects
Related Articles
Gender differences in adiponectin and low-grade inflammation among individuals with normal glucose tolerance, prediabetes, and type 2 diabetes
Gender Medicine, 10/21/09
Relevance Score: 97%
Does rheumatoid arthritis equal diabetes mellitus as an independent risk factor for cardiovascular disease? A prospective study
Arthritis Care and Research, 11/03/09
Relevance Score: 96%
Value of C-reactive protein and IL-6 measurements in type 1 diabetes mellitus
Archives of Medical Science, 11/02/09
Relevance Score: 96%
Age-Associated Increase in Abdominal Obesity and Insulin Resistance, and Usefulness of AHA/NHLBI Definition of Metabolic Syndrome for Predicting Cardiovascular Disease in Japanese Elderly with Type 2 Diabetes Mellitus
Gerontology, 10/19/09
Relevance Score: 96%
Defining the Importance of Daily Glycemic Control and Implications for Type 2 Diabetes Management
Postgraduate Medicine, 10/05/09
Relevance Score: 96%
Today in Atherosclerosis/Lipids...keeping you current
Receive free subspecialty "5-minute updates" via email
Smoking intensity and lipoprotein abnormalities in active smokers
Journal of Clinical Lipidology, 12/18/09
Cost-effectiveness analysis of the use of a high-intensity statin compared to a low-intensity statin in the management of patients with familial hypercholesterolaemia
Current Medical Research and Opinion, 12/18/09
Walking Speed and Subclinical Atherosclerosis in Healthy Older Adults: The Whitehall Ii Study
Heart, 12/18/09
Today in Complementary Medicine...keeping you current
Receive free subspecialty "5-minute updates" via email
Hibiscus Sabdariffa L. Tea (Tisane) Lowers Blood Pressure in Prehypertensive and Mildly Hypertensive Adults
The Journal of Nutrition, 12/18/09
Promotion of direct angiogenesis in vitro and in vivo by Puerariae flos extract via activation of MEK/ERK-, PI3K/Akt/eNOS-, and Src/FAK-dependent pathways
Phytotherapy Research, 12/16/09
Evaluation of prescribing patterns in a German network of CAM physicians for the treatment of patients with hypertension: a prospective observational study
BMC Family Practice, 12/14/09
Sponsor
Article Search
Sponsor
Sponsor