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KLF2 Primes the Antioxidant Transcription Factor Nrf2 for Activation in Endothelial Cells
Arteriosclerosis, Thrombosis, and Vascular Biology, 05/09/08

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Fledderus JO et al. - We report that KLF2 substantially enhances antioxidant activity of Nrf2 by increasing its nuclear localization and activation. The synergistic activity of these two transcription factors forms a major contribution to the shear stress–elicited transcriptome in endothelial cells.

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