Usefulness of the SYNTAX score for predicting clinical outcome after percutaneous coronary intervention of unprotected left main coronary artery disease
Capodanno D et al. – The SYNTAX score (SXscore) is a useful tool to predict cardiac mortality and major adverse cardiac events (MACE) in pts undergoing percutaneous revascularization of the left main coronary artery. Methods- Application of SXscore in 255 consecutive pts who had percutaneous coronary intervention for left main disease
- Assessment of SXscore performance related to clinical outcome
- Univariate and multivariate Cox proportional hazard regression analyses to evaluate relation between SXscore and incidence of cardiac mortality and MACE
- Primary endpoint: relation between SXscore and incidence of cardiac mortality
Results- At 1 yr, SXscore significantly predicted risk of cardiac death and MACE
- After adjustment for potential confounders, a higher SXscore remained significantly associated with cardiac mortality and MACE
- C-indexes for SXscores for cardiac death and MACE: 0.83 and 0.64, respectively
- Using classification tree analysis, discrimination levels of 34 and 37 identified as optimal cutoff to distinguish between pts at low and high risk of cardiac death and MACE, respectively
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