Resveratrol Blocks Interleukin-18-EMMPRIN Crossregulation and Smooth Muscle Cell Migration
Venkatesan B et al. - The results demonstrate that coexpression and regulation of IL-18 and EMMPRIN in the vessel wall may amplify the inflammatory cascade and promote atherosclerosis and remodeling. Resveratrol, via its antioxidant and anti-inflammatory properties, has the potential to inhibit the progression of atherosclerosis by blocking IL-18 and EMMPRIN crossregulation and SMC migration. [more...]
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