Cardiac protection takes off
Piper HM et al. - Cardiac malfunction and manifest tissue damage after ischaemia–reperfusion may be due to events during ischaemia as well as additional ones during reperfusion, and different routes of protection need to be considered for the (pre)ischaemic or post-ischaemic period. The known mechanisms of protection include targets in specific intracellular signalling pathways, functions of intracellular organelles such as sarcoplasmic reticulum and mitochondria, and control of intracellular ion homeostasis. [more...]
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