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See Latest ArticlesCharacterisation of the activated liver progenitor cell niche, potential involvement of Wnt and Notch signalling
Gut, 11/09/09
Spee B et al. – A distinct pattern of HPC surface markers was found between acute– and chronic–liver diseases. Similar to what is known from experiments, strong evidence has been found signifying the role of Wnt signalling in proliferation of human HPCs whereas Notch signalling is involved in biliary differentiation. These pathways can be targeted in future therapies.
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