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New Insights into Whipple's Disease - A Rare Intestinal Inflammatory Disorder
Digestive Diseases, 11/09/09

Marth T – Several studies show that subtle defects of the cell–mediated immunity exist in active and inactive WD which may predispose individuals with a certain HLA type to a clinical manifestation of T. whipplei infection. As confirmed in a recent controlled trial, most patients respond well to a prolonged antibiotic treatment, but some patients with relapsing disease or CNS manifestation may have a poor prognosis. In the presentation, the relevance of WD in the differential diagnosis of chronic diarrhea and the new findings of this enigmatic rare disorder will be discussed.

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