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See Latest ArticlesAnalysis of Candidate Genes in Occurrence and Growth of Colorectal Adenomas
Journal of Oncology, 11/02/09
Olschwang S et al. – Predisposition to sporadic colorectal tumours is influenced by genes with minor phenotypic effects. A case–control study was set up on 295 patients treated for a large adenoma matched with polyp–free individuals on gender, age, and geographic origin in a 1 : 2 proportion. The APC p.Glu1317Gly variant appeared to influence the adenoma growth (P=.04, exact test) but not its occurrence. This result needs to be replicated and genome–wide association studies may be necessary to fully identify low–penetrance alleles involved in early stages of colorectal tumorigenesis.
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A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma
American Journal of Clinical Nutrition, 10/29/09
Localized resection for colon cancer
Surgical Oncology, 11/04/09
Treatment of Fistulizing Inflammatory Bowel Disease
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