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Novel hepatitis B virus subgenotype A6 in African-Belgian patients
Journal of Clinical Virology, 10/27/09
Pourkarim MR et al. – Phylogenetic analysis of the complete genome sequences yielded maximal bootstrap value support for nodes that establish the new lineage as a novel subgenotype. In addition, nucleotide divergence more than 4% based on full–length genome of the virus, clearly demonstrated that the three African–Belgian strains belonged to a novel subgenotype of HBV, which was assigned as “A6”. Noteworthy, the phylogeny of genotype A demonstrated that the A6 is a basal lineage that diverged earlier from the other African subgenotypes of genotype A.
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