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Amphiregulin Induces the Alternative Splicing of p73 Into Its Oncogenic Isoform Ex2p73 in Human Hepatocellular Tumors
Gastroenterology, 10/29/09

Castillo J et al. – The study provided a mechanism for the generation of protumorigenic Ex2p73 during liver tumorigenesis, via activation of EGFR signaling by AR and c–Jun N–terminal kinase–1 activity, leading to inhibition of the splicing regulator Slu7.

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