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MDP-NOD2 stimulation induces HNP-1 secretion, which contributes to NOD2 antibacterial function
Inflammatory Bowel Disease, 10/26/09
Podolsky DK et al. – HNP–1 secretion depends on NOD2 stimulation by MDP–LD and contributes to antibacterial activity in intestinal epithelial cells expressing endogenous NOD2, but not NOD2 3020insC mutant associated with increased susceptibility to Crohn's disease.
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