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See Latest ArticlesHomozygous P86S Mutation of the Human Glucagon Receptor Is Associated With Hyperglucagonemia, [alpha] Cell Hyperplasia, and Islet Cell Tumor
Pancreas, 10/26/09
Zhou C et al. – The authors report the first homozygous missense mutation in the human GCGR, which is associated with alpha cell hyperplasia and hyperglucagonemia. This mutation lowers the receptor's affinity to glucagon and decreases cyclic adenosine monophosphate production with physiological concentrations of glucagon. Thus, the P86S mutation in GCGR likely causes alpha cell hyperplasia and hyperglucagonemia.
Today in Basic Science/Genetics...keeping you current
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Joint Extraintestinal Manifestations in Ulcerative Colitis
Digestive Diseases, 11/09/09
The liver in 30-year-old individuals with alpha 1 -antitrypsin deficiency
Scandinavian Journal of Gastroenterology, 11/06/09
Caspase-cleaved fragments of cytokeratin 18 - the promises and challenges of a biomarker for chronic liver disease
Alimentary Pharmacology and Therapeutics, 11/03/09
Today in Biliary System/Pancreas...keeping you current
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Novel Pancreaticojejunostomy with a Low Rate of Anastomotic Failure-Related Complications
Journal of the American College of Surgeons, 10/30/09
Day case laparoscopic cholecystectomy is feasible
Irish Journal of Medical Science, 11/02/09
Gemcitabine, oxaliplatin and 5-FU in advanced bile duct and gallbladder carcinoma: two parallel, multicentre phase-II trials
British Journal of Cancer, 11/13/09
Today in GI Oncology...keeping you current
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Treatment of Fistulizing Inflammatory Bowel Disease
Gastroenterology Clinics of North America, 11/13/09
Safety Profile of IBD: Lymphoma Risks
Gastroenterology Clinics of North America, 11/16/09
Image-enhanced endoscopy in practice
Canadian Journal of Gastroenterology, 11/06/09
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