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Hepatitis B reactivation in allogeneic hemopoietic stem cell transplantation setting: A pediatric experience
Pediatric Transplantation, 10/20/09

Faraci M et al. – This experience confirms that HBV–DNA may persist as intra–hepatic infection or in extra–hepatic sites and that HBV reactivation may appear during immunodepression. Careful and complete screening for HBV markers is mandatory before HSCT, especially in children coming from countries at risk for HBV. Furthermore, a treatment with lamivudine could also represent an efficacious prophylaxis in pediatric patients to avoid HBV reactivation and to decrease the development of severe hepatic disease.

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