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Koppler H et al. – Due to necessary selection criteria, the results obtained in clinical trials may not reflect the actual impact of current treatment options for unselected general populations. The authors analysed the treatment modalities and the outcome in 206 consecutive patients with advanced colorectal cancer who started treatment between 1/1999 and 11/2004. The increased survival seen in prospective studies can be transferred to routine care for unselected patients with advanced colorectal cancer.

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