Gastro Medical News about Anal Canal

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Review of 120 anal cancer patients
Colorectal Disease, 10/15/09

Solomon MJ et al. – Chemoradiation is effective organ preserving treatment for anal cancer. Grade 1 and 2 faecal incontinence is a relatively common late toxicity experienced by patients.

Exclusive Author Commentary
Selena C Young, 10/23/09

As organ function preservation is an important objective of chemoradiation for anal cancer, the relatively high rates of low grade faecal incontinence is a concern. The randomised trials in anal cancer have not detailed faecal incontinence well. Prospective recording of faecal continence rates in future studies of anal cancer, with baseline spincter function or anal manometry would be useful in evaluating the functional impact of chemoradiation.

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Effects of ovarian failure on submucosal collagen and blood vessels of the anal canal in postmenopausal women
International Journal of Colorectal Disease, 11/12/09 Relevance Score: 67%

Muscle Derived Cell Injection to Treat Anal Incontinence due to Obstetric Trauma: Pilot Study with One-Year Follow-Up
Gut, 11/09/09 Relevance Score: 67%

Anal stenosis: use of an algorithm to provide a tension-free anoplasty
Australian and New Zealand Journal of Surgery, 10/12/09 Relevance Score: 66%

Lack of correlation between p53 codon 72 polymorphism and anal cancer risk
World Journal of Gastroenterology, 10/07/09 Relevance Score: 66%

Malignant melanoma of the anal canal
Journal of Contemporary Brachytherapy, 10/13/09 Relevance Score: 65%