Gastro Medical News about fluorouracil

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Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma
International Journal of Medical Sciences , 10/14/09

Kuwahara A et al. – The circadian rhythm in plasma concentrations of 5–FU observed in the case of CDDP was altered when NDP was used instead. The clinical response can be predicted by monitoring plasma concentrations of 5–FU in the CDDP group, but not in the NDP group.

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