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Elevated Systemic Hepcidin and Iron Depletion in Obese Premenopausal Females
Obesity, 10/14/09

Tussing–Humphreys LM et al. – The source of excess hepcidin appears to be the liver and not adipose tissue. The ID of obesity is predominantly a condition of a true body iron deficit rather than maldistribution of iron due to inflammation. However, these findings suggest inflammation may perpetuate this condition by hepcidin–mediated inhibition of dietary iron absorption.

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