Gastro Medical News about Gastroesophageal Reflux

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The GABAB receptor agonist AZD9343 inhibits transient lower oesophageal sphincter relaxations and acid reflux in healthy volunteers: a phase I study
Alimentary Pharmacology and Therapeutics, 10/09/09

Boeckxstaens GE et al. – Like baclofen, AZD9343 dose–dependently decreases the number of TLESRs and acid reflux episodes, increases LES pressure and reduces swallowing, extending the concept that GABAB agonists are potent reflux inhibitors. However, discovery of analogues with an improved side effect profile is warranted.

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Gastroesophageal Reflux Might Cause Esophagitis Through a Cytokine-Mediated Mechanism Rather Than Caustic Acid Injury
Gastroenterology, 10/28/09 Relevance Score: 68%

Gastroesophageal reflux in mechanically ventilated pediatric patients and its relation to ventilator-associated pneumonia
Critical Care, 10/27/09 Relevance Score: 68%

Upper Esophageal Sphincter and Gastroesophageal Junction Pressure Changes Act to Prevent Gastroesophageal and Esophagopharyngeal Reflux during Apneic Episodes in Patients with Obstructive Sleep Apnea
Chest, 11/17/09 Relevance Score: 67%

Evaluating outcomes of endoscopic full-thickness plication for gastroesophageal reflux disease with impedance monitoring
Surgical Endoscopy, 11/16/09 Relevance Score: 67%

Trends in Gastroesophageal Reflux Disease as Measured by the National Ambulatory Medical Care Survey
Digestive Diseases and Sciences, 10/27/09 Relevance Score: 67%