Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Use of Antiemetic Agents in Acute Gastroenteritis 3. 2008 Exclusive Survey—Earnings: Good news for primary care income 4. A randomised phase III study on capecitabine, oxaliplatin and bevacizumab with or without cetuximab in first-line advanced colorectal cancer, the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG). An interim analysis of toxicity 5. Medicare pay-for-reporting effort draws fire from frustrated doctors
Your Article Summary
Induction and Down-regulation of Sox17 and Its Possible Roles During the Course of Gastrointestinal Tumorigenesis
Gastroenterology, 10/07/09
Du YC et al. – Sox17 plays a tumor suppressor role through suppression of Wnt signaling. However, Sox17 is induced by Wnt activation in the early stage of gastrointestinal tumorigenesis, and Sox17 is down–regulated by methylation during malignant progression. It is therefore conceivable that Sox17 protects benign tumors from malignant progression at an early stage of tumorigenesis, and down–regulation of Sox17 contributes to malignant progression through promotion of Wnt activity.
Related Articles
APC promoter hypermethylation is an early event in endometrial tumorigenesis
Cancer Science, 11/16/09
Relevance Score: 88%
RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1
Oncogene, 10/26/09
Relevance Score: 88%
Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapy
Journal of Hematology & Oncology, 10/30/09
Relevance Score: 85%
High Expression of the PAX3-FKHR Oncoprotein Is Required to Promote Tumorigenesis of Human Myoblasts
American Journal of Pathology, 11/09/09
Relevance Score: 83%
EBV-Induced Human CD8+ NKT Cells Suppress Tumorigenesis by EBV-Associated Malignancies
Cancer Research, 10/21/09
Relevance Score: 82%
Today in Basic Science/Genetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Variants in the UGT1A1 Gene and the Risk of Pediatric Nonalcoholic Fatty Liver Disease
Pediatrics, 12/02/09
p53 Genotype Predicts Response to Chemotherapy in Patients with Squamous Cell Carcinoma of the Esophagus
Annals of Surgical Oncology, 12/02/09
Protective Effects of Early CD4+ T Cell Reduction in Hepatic Ischemia/Reperfusion Injury
Journal of Gastrointestinal Surgery, 12/02/09
Today in GI Oncology...keeping you current
Receive free subspecialty "5-minute updates" via email
Surgical treatment of hepatic tumors in children: lessons learned from liver transplantation
Journal of Pediatric Surgery, 12/02/09
EpCAM: A Potential Antimetastatic Target for Gastric Cancer
Digestive Diseases and Sciences, 12/02/09
Ratio Between Metastatic and Examined Lymph Nodes (N Ratio) May Have Low Clinical Utility in Gastric Cancer Patients Treated by Limited Lymphadenectomy: Results from a Single-Center Experience of 526 Patients
World Journal of Surgery, 12/02/09
Sponsor
Article Search
Sponsor


See Latest Articles


