Gastro Medical News about Liver Transplantation

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Recurrence of Bile Salt Export Pump Deficiency after Liver Transplantation
New England Journal of Medicine, 10/01/09

Jara P et al. – The phenotypic recurrence of the disease correlated with the presence of circulating high–titer antibodies against BSEP that inhibit transport by BSEP in vitro. When administered to rats, these antibodies targeted the bile canaliculi and impaired bile acid secretion.

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