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Donor mannose-binding lectin gene polymorphisms influence the outcome of liver transplantation
Liver Transplantation, 09/30/09
Cervera C et al. – Liver transplantation from a donor with a variant MBL2 exon 1 genotype was associated with a worse prognosis, mainly because of infections of higher severity.
Carlos Cervera, 09/30/09
| Based on the results of our research, liver graft donors MBL2 genotype determination could be useful to stratify the risk of infection and infection-related death after liver transplantation. Recipients of a liver from a MBL2 defficient genotypes donor should be closely monitorized. |
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