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See Latest ArticlesVariability in the upper limit of normal for serum alanine aminotransferase levels: A statewide study
Hepatology, 09/30/09
Chalasani N et al. – Wide variability in ALT ULN across different labs is more likely due to variable reference intervals of different chemical analyzers. It may be possible to minimize variability in ALT ULN by each lab solely following the manufacturers' recommendations and manufacturers of different analyzers following consistent and rigorous methodology in establishing the reference range. Alternatively, studies should be undertaken to identify outcome–based reference intervals for ALT.
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