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Practical pathology and genetics of Hirschsprung's disease
Seminars in Pediatric Surgery, 10/07/09
Kapur RP – Critical consideration of transition zone anatomy and published studies of "transition zone pull through" indicate that more research is needed to determine how much ganglionic bowel should be resected from HSCR patients. Many HSCR–susceptibility genes have been identified, but mutational analysis has limited practical value unless family history or clinical findings suggest syndromic HSCR.
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