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See Latest ArticlesButyrate utilization by the colonic mucosa in inflammatory bowel diseases: A transport deficiency
Inflammatory Bowel Disease, 09/25/09
Thibault R et al. – Recent data show that butyrate deficiency results from the reduction of butyrate uptake by the inflamed mucosa through downregulation of the monocarboxylate transporter MCT1. The concomitant induction of the glucose transporter GLUT1 suggests that inflammation could induce a metabolic switch from butyrate to glucose oxidation. Butyrate transport deficiency is expected to have clinical consequences.
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