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Finucane FM et al. – The leptin:adiponectin ratio is a useful measure of insulin resistance in non–diabetic white adults. These data highlight the central role of adipocyte dysfunction in the pathogenesis of insulin resistance. Given that variations between fasting and postprandial leptin and adiponectin levels tend to be small, the leptin to adiponectin ratio might also have potential value in assessing insulin sensitivity in the non–fasted state.

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