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See Latest Articlesp21 Expression in Colon Cancer and Modifying Effects of Patient Age and Body Mass Index on Prognosis
Cancer Epidemiology, Biomarkers & Prevention, 09/14/09
Ogino S et al. – p21 loss in colon cancer is associated with longer survival among patients >=60 year old, whereas it is associated with shorter survival among patients <60 year old. Patient BMI also differentially influences prognosis according to p21 CDKN1A status. The data suggest host–tumor interactions influencing tumor aggressiveness.
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