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See Latest ArticlesPharmacogenomics in chemotherapy for GI tract cancer
Journal of Gastroenterology, 09/08/09
Furuta T et al. – In GI–tract cancer chemotherapy, 5–FU, gemcitabine, taxanes (docetaxel and paclitaxel), platinum (cisplatin and oxaliplatin) and irinotecan are often used, and molecular targeting therapy has also been developed. The respective PGx markers to such agents have been reported. Of the candidate PGx markers, K–ras mutation and UGT1A1 polymorphisms have sufficient evidence to justify routine clinical assessment for the selection of anti–cancer regimens.
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Today in Pharmacology/kinetics...keeping you current
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ML17032 trial: capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in advanced gastric cancer
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