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Effect of Zolpidem on the Sleep Arousal Response to Nocturnal Esophageal Acid Exposure
Clinical Gastroenterology and Hepatology , 09/04/09
Gagliardi GS et al. – Zolpidem reduced the arousal response to nocturnal acid exposure and increased the duration of each esophageal acid reflux event in healthy individuals and patients with GER. Because nocturnal acid exposure was prolonged, hypnotic use by patients with GER could lead to increased risk for complicated disease.
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