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See Latest ArticlesAntigen-presenting cells exposed to Lactobacillus acidophilus NCFM, Bifidobacterium bifidum BI-98, and BI-504 reduce regulatory T cell activity
Inflammatory Bowel Disease, 09/03/09
Kristensen NN et al. – The authors conclude that certain probiotic strains can modify APCs to cause reduced Treg activity. This effect apparently depends on a direct APC–to–Treg cell contact. The APC–mediated suppressive effect on Treg function of certain probiotic strains may constrain the anti–inflammatory activity, which is often desired from probiotic therapy. This unexpected function of certain probiotic strains should be taken into consideration when designing adjuvant therapies with these bacteria, or when probiotic strains are selected for improvement of gut–associated inflammation like IBD.
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Today in Basic Science/Genetics...keeping you current
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Polymorphisms of the apoptosis-associated gene DP1L1 (deleted in polyposis 1-like 1) in colon cancer and inflammatory bowel disease
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Today in Inflammatory Bowel Dz...keeping you current
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