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Current Pharmacological Management of Gastro-Esophageal Reflux in Children: An Evidence-Based Systematic Review
Pediatric Drugs, 07/28/09

Tighe MP et al. – Gaviscon Infant sachets are safe and can improve symptoms of reflux. There is less evidence to support the use of domperidone or metoclopramide. More evidence is needed before other anti–reflux medications can be recommended. For older children, acid suppression is the mainstay of treatment. The largest evidence base supports the early use of H2 receptor antagonists or proton pump inhibitors.

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