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Involvement of JNK pathway in the promotion of the early stage of colorectal carcinogenesis under high-fat dietary condition
Gut, 07/06/09
Nakajima A et al. - Colonic cell proliferation was promoted via the JNK pathway in the presence of a HFD but not in the presence of a ND. This novel mechanism may explain the involvement of the JNK pathway in the effect of dietary fat intake on colon carcinogenesis.
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