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Nuclear Pregnane X Receptor Single Nucleotide Polymorphism (-25385C/T) Is Not Associated With Inflammatory Bowel Disease in Pediatric Patients
Journal of Pediatric Gastroenterology and Nutrition, 07/01/09

Lacher M et al. - Although no significant differences were seen between the genotypes. PXR was underexpressed in colonic tissue of 7 out of 11 Crohn disease and in 4 out of 5 patients with ulcerative colitis. The authors could not confirm an association of the -25385C/T polymorphism in pediatric patients with IBD.

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