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Thiazolidinediones for the Treatment in NASH: Sustained Benefit After Drug Discontinuation
Journal of Clinical Gastroenterology, 06/19/09
Argo CK et al. - The authors conclude that sustained histologic response after short-term TZD therapy for NASH is not invariably lost after medication discontinuation but rather is intimately related to sustained changes in lifestyle, particularly physical activity. Activity and diet in the setting of thiazolidinedione or other drug therapy of NASH is an essential consideration that warrants careful incorporation into future drug trials.
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