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Rifampicin as an Oral Angiogenesis Inhibitor Targeting Hepatic Cancers
Cancer Research, 06/02/09
Shichiri M et al. - The potent antiangiogenic properties of oral rifampicin therapy were effective in suppressing cancer progression. It provides a promising new addition to antiangiogenic strategies for designing human cancer therapies. Considering the clinical pharmacokinetics of rifampicin, which enters the enterohepatic circulation and undergoes subsequent hepatic accumulation, it may be especially beneficial as an antitumor agent targeting hepatobiliary tumors.
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