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Uncoupling of sympathetic nervous system and hypothalamic-pituitary-adrenal axis in cirrhosis
Journal of Gastroenterology and Hepatology, 12/03/08
Wiest R et al. - The present study demonstrates that the two stress axes seem to act in parallel fashion in control subjects but are uncoupled in liver cirrhosis. Authors discuss how uncoupling of the two anti-inflammatory axes can occur and may contribute to the increased susceptibility for infections and lethal complications in cirrhotic patients.
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