Sitafloxacin Activity against Helicobacter pylori Isolates, Including Those with gyrA Mutations Murakami K et al. - Sitafloxacin showed MICs of less than or equal to 0.5 µg/ml against 105 isolates of Helicobacter pylori, including 44 isolates with mutations in the gyrA gene. The highest MICs for garenoxacin and levofloxacin were 8 and 64 times, respectively, higher than the highest MICs observed for sitafloxacin. [more...]