Up-regulation of dbpA mRNA in hepatocellular carcinoma associated with metabolic syndrome

Hepatology International, 04/09/2012

This study identifies that DNA–binding protein A (dbpA) may accelerate the hepatocarcinogenesis in hepatocellular carcinoma (HCC) patients with metabolic syndrome (MS) via inflammation–induced and oxidative stress pathways. The demethylation–related epigenetic activation may be one of the regulating factors for HCC patients with MS.

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