Does adjuvant steroid therapy post-Kasai portoenterostomy improve outcome of biliary atresia? Systematic review and meta-analysis
Canadian Journal of Gastroenterology, 08/29/2011
Evidence Based Medicine
Clinical Article
Sarkhy A et al. – The present meta–analysis did not find a significant effect of steroid over standard therapy, either in normalizing serum bilirubin levels at six months or at delaying the need for early liver transplantation post–Kasai portoenterostomy(KP). Randomized controlled triat(RCT) studies of sufficient size and comprehensive design using high–dose steroids are needed to determine the effectiveness of steroids on the short and intermediate post–KP outcomes for biliary atresia(BA) patients.





