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541 Determinants of Hepatitis C Virus Treatment Completion and Efficacy in Drug Users Assessed by Meta-analysis Clinical Infectious Diseases, January 9, 2013 Evidence Based Medicine Clinical Article
542 Hepatocellular carcinoma treated with sorafenib: early detection of treatment response and major adverse events by contrast-enhanced US Liver International, January 9, 2013 Clinical Article
543 Long-term treatment of patients with a history of ulcerative colitis who develop gastritis and pan-enteritis after colectomy Journal of Clinical Gastroenterology, January 9, 2013 Clinical Article
544 Meta-analysis of the efficacy and safety of lactobacillus-containing and bifidobacterium-containing probiotic compound preparation in helicobacter pylori eradication therapy Journal of Clinical Gastroenterology, January 9, 2013 Evidence Based Medicine Clinical Article
545 Coupled plasma filtration adsorption combined with continuous veno-venous hemofiltration treatment in patients with severe acute pancreatitis Journal of Clinical Gastroenterology, January 9, 2013 Clinical Article
546 XRCC1 and GSTP1 polymorphisms and prognosis of oxaliplatin-based chemotherapy in colorectal cancer: a meta-analysis Cancer Chemotherapy and Pharmacology, January 9, 2013 Evidence Based Medicine Clinical Article
547 MAPK signaling in cisplatin-induced death: predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells Carcinogenesis, January 9, 2013 Clinical Article
548 Exploratory Study of Oral Combination Antiviral Therapy for Hepatitis C New England Journal of Medicine, January 8, 2013 Clinical Article
549 High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury Hepatology, January 8, 2013 Clinical Article
550 Functional constipation in childhood: current pharmacotherapy and future perspectives Expert Opinion on Pharmacotherapy, January 8, 2013 Clinical Article
551 Safety, pharmacokinetics and pharmacodynamics of the anti-A33 fully-human monoclonal antibody, KRN330, in patients with advanced colorectal cancer European Journal of Cancer, January 8, 2013 Clinical Article
552 Clofibrate in combination with phototherapy for unconjugated neonatal hyperbilirubinaemia Cochrane Reviews, January 8, 2013 Clinical Article
553 Compatibility of intravenous medications with parenteral nutrition Journal of Parenteral and Enteral Nutrition, January 8, 2013 Clinical Article
554 Tacrolimus pharmacokinetics in the early post-liver transplantation period and clinical applicability via Bayesian prediction European Journal of Clinical Pharmacology, January 8, 2013 Clinical Article
555 Tenofovir rescue therapy for chronic hepatitis B patients after multiple treatment failures Full Text World Journal of Gastroenterology, January 7, 2013 Clinical Article
556 Efficacy and Safety of Pegylated Interferon Alfa-2a or Alfa-2b Plus Ribavirin for the Treatment of Chronic Hepatitis C in Children and Adolescents: A Systematic Review and Meta-analysis Clinical Infectious Diseases, January 7, 2013 Evidence Based Medicine Clinical Article
557 Anticoagulant therapy in patients with non-cirrhotic portal vein thrombosis: effect on new thrombotic events and gastrointestinal bleeding Journal of Thrombosis and Haemostasis, January 7, 2013 Clinical Guideline Clinical Article
558 ABL Regulation by AXL Promotes Cisplatin Resistance in Esophageal Cancer Cancer Research, January 7, 2013 Clinical Article
559 Gut microbiota disturbance during antibiotic therapy: a multi-omic approach Gut, January 7, 2013 Clinical Article
560 Effects of Omeprazole on Vitamin and Mineral Absorption and Metabolism Journal of Pharmacy Technology, January 7, 2013 Clinical Article
As published in the NEJM, researchers in the COLONPREV study (Spain) have reported that fecal immunochemical testing (FIT) is as effective as colonoscopy in the detection of colorectal cancer (CRC). The study population was 50-69 years of age and comprised of 26,703 subjects who underwent a one-time colonoscopy and 26,599 subjects who underwent FIT every 2 years. The primary outcome measure was CRC deaths at 10 years. Participation in screening was greater in the FIT group than the colonoscopy group (34.2% vs. 24.6%). Detection of CRC was similar between the two groups (0.1%). Advanced and non-advanced adenomas were detected more frequently in the colonoscopy group than the FIT group (1.9% vs. 0.9% [OR=2.3] and 4.2% vs. 0.4% [OR=9.8], respectively).
Read the article summaryBased on a meta-analysis involving 30 observational studies and 202,965 patients, proton pump inhibitor therapy has been shown to significantly increase the risk of infection with Clostridium difficile (OR = 2.15).
Read the article summaryIn a single institution study involving 424 patients with DM and CRC, those patients treated with metformin had a 30% improvement in OS compared with patients not treated with metformin. Specifically, the metformin-treated patients had a mean survival of 76.9 months compared to 56.9 months.
Read the article summary1 Ischemic Colitis with Type I Interferons Used in the Treatment of Hepatitis C and Multiple Sclerosis: An Evaluation from the Food and Drug Administration Adverse Event Reporting System and Review of the Literature Annals of Pharmacotherapy, April 3, 2013 Review Article
2 Treatment for H. pylori Infection: New Challenges With Antimicrobial Resistance Journal of Clinical Gastroenterology, April 11, 2013
3 Efficacy of Two Levofloxacin-Containing Second-Line Therapies for Helicobacter pylori: A Pilot Study Helicobacter, April 24, 2013
4 The effect of Helicobacter pylori infection and eradication in patients with gastro-oesophageal reflux disease: A parallel-group, double-blind, placebo-controlled multicentre study United European Gastroenterology Journal, April 1, 2013
5 Management of difficult-to-treat patients with ulcerative colitis: focus on adalimumab Drug Design, Development and Therapy, April 10, 2013 Free full text
6 Incidence of Campylobacter and Salmonella Infections Following First Prescription for PPI: A Cohort Study Using Routine Data The American Journal of Gastroenterology, April 17, 2013
7 Propofol for Pediatric Colonoscopy: The Experience of a Large, Tertiary Care Pediatric Hospital American Journal of Therapeutics, April 15, 2013
8 Adalimumab combined with ciprofloxacin is superior to adalimumab monotherapy in perianal fistula closure in Crohns disease: a randomised, double-blind, placebo controlled trial (ADAFI) Gut, April 9, 2013
9 Impact of oral silymarin on virus- and non-virus-specific T-cell responses in chronic hepatitis C infection Journal of Viral Hepatitis, April 16, 2013
10 Dysmotility and proton pump inhibitor use are independent risk factors for small intestinal bacterial and/or fungal overgrowth Alimentary Pharmacology and Therapeutics, April 15, 2013
11 Dual oral therapy with daclatasvir and asunaprevir for patients with HCV genotype 1b infection and limited treatment options Journal of Hepatology, April 2, 2013
12 Clinical utility of newly developed immunoassays for serum concentrations of adalimumab and anti-adalimumab antibodies in patients with Crohns disease Journal of Gastroenterology, April 15, 2013
13 Long term benefit of one year infliximab administration for the treatment of chronic refractory pouchitis Journal of Crohn's and Colitis, April 5, 2013
14 Cost-per-remission analysis of infliximab compared to adalimumab among adults with moderate-to-severe ulcerative colitis Journal of Medical Economics , April 16, 2013 Review Article
15 Anti-Tumor Necrosis Factor Therapy Is Associated With Infections after Abdominal Surgery in Crohn's Disease Patients The American Journal of Gastroenterology, March 19, 2013
16 Diagnostic difficulties, therapeutic strategies, and performance of scoring systems in patients with autoimmune hepatitis and concurrent hepatitis B/C Scandinavian Journal of Gastroenterology, April 17, 2013
17 Randomised clinical trial: macrogol/PEG 3350+electrolytes versus prucalopride in the treatment of chronic constipation - a comparison in a controlled environment Alimentary Pharmacology and Therapeutics, March 20, 2013
18
Infliximab versus cyclosporine as rescue therapy in acute severe steroid-refractory ulcerative colitis: a systematic review and meta-analysis
International Journal of Colorectal Disease, March 18, 2013
Evidence Based Medicine
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19 Comparison Between Botulinum Injection and Removable Covered Self-Expanding Metal Stents for the Treatment of Achalasia Digestive Diseases and Sciences, February 28, 2013
20 Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis Drug Design, Development and Therapy, April 26, 2013 Free full text Review Article
Indexed Journals in Gastroenterology: Gastroenterology, American Journal of Gastroenterology, Gut more
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