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Gastroenterology - Pharmacology/kinetics News & Articles

Available now at MDLinx Gastroenterology: Ranked summaries of the most clinically-relevant GI literature refreshed every 24 hours, as well as MDLinx Gastroenterology exclusive content

  • Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in your uniquely diverse field. In addition to general gastroenterology news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.
  • MDLinx Gastroenterology exclusive content includes: Monthly highlights of the "can't miss" articles chosen by our physician editor, D. Scott Cunningham, MD, PhD; clinical pearls from The Smartest Internist and Smartest Family Physician daily competitions, a collaboration from the editors of MDLinx and Cleveland Clinic Center for Continuing Education; and pearls from our Pediatrics Physician Review quizzes.

Your Unread Messages in Gastroenterology

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Articles

Latest (4) Full Text Articles (194)
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

361 Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial British Journal of Anesthesia, February 28, 2013    Clinical Article

362 Primary sclerosing cholangitis: a review and update on therapeutic developments Expert Review of Gastroenterology & Hepatology, February 28, 2013    Review Article    Clinical Article

363 Comparison Between Botulinum Injection and Removable Covered Self-Expanding Metal Stents for the Treatment of Achalasia Digestive Diseases and Sciences, February 28, 2013    Clinical Article

364 Efficacy of Cholestyramine Ointment in Reduction of Postoperative Pain and Pain during Defecation after Open Hemorrhoidectomy: Results of a Prospective, Single-center, Randomized, Double-blind, Placebo-controlled Trial World Journal of Surgery, February 27, 2013    Clinical Article

365 Diabetic gastroparesis: recent insights into pathophysiology and implications for management Expert Review of Gastroenterology & Hepatology, February 27, 2013    Clinical Article

366 IL28B polymorphisms predict the virological response to standard therapy in patients with chronic hepatitis C virus genotype 4 infection Hepatology International, February 27, 2013    Clinical Article

367 Defensive medicine practices among gastroenterologists in Lombardy: Between lawsuits and the economic crisis Digestive and Liver Diseases, February 27, 2013    Clinical Article

368 FDA approves first drug in over a decade for prevention of organ rejection Full Text Drug Topics, February 27, 2013    Clinical Article

369 Oleanolic acid and ursolic acid: novel Hepatitis C virus antivirals that inhibit NS5B activity Antiviral Research , February 26, 2013    Clinical Article

370 Bevacizumab as Rescue Treatment for Severe Recurrent Gastrointestinal Bleeding in Hereditary Hemorrhagic Telangiectasia Journal of Clinical Gastroenterology, February 26, 2013    Clinical Article

371 Nonbismuth Quadruple “Concomitant” Therapy Versus Standard Triple Therapy, Both of the Duration of 10 Days, for First-Line H. Pylori Eradication: A Randomized Trial Journal of Clinical Gastroenterology, February 25, 2013    Clinical Article

372 Intensified Peginterferon α-2a Dosing Increases Sustained Virologic Response Rates in Heavy, High Viral Load Hepatitis C Genotype 1 Patients With High Low-density Lipoprotein Journal of Clinical Gastroenterology, February 25, 2013    Clinical Article

373 Randomised clinical trial: vancomycin or metronidazole in patients with primary sclerosing cholangitis - a pilot study Alimentary Pharmacology and Therapeutics, February 25, 2013    Clinical Article

374 Comparison of modified percutaneous transhepatic variceal embolization and endoscopic cyanoacrylate injection for gastric variceal rebleeding Full Text World Journal of Gastroenterology, February 25, 2013    Clinical Article

375 Rifaximin in the Treatment of Irritable Bowel Syndrome: Is There a High Risk for Development of Antimicrobial Resistance Journal of Clinical Gastroenterology, February 22, 2013    Clinical Article

376 The use of abdominal muscle training, breathing exercises and abdominal massage to treat pediatric chronic functional constipation Colorectal Disease, February 22, 2013    Clinical Article

377 Pharmacokinetics of cisplatin during hyperthermic intraperitoneal treatment of peritoneal carcinomatosis European Journal of Clinical Pharmacology, February 22, 2013    Clinical Article

378 Effect of ribavirin on viral kinetics and liver gene expression in chronic hepatitis C Gut, February 22, 2013    Review Article

379 Can mosapride citrate reduce the volume of lavage solution for colonoscopy preparation Full Text World Journal of Gastroenterology, February 22, 2013    Clinical Article

380 Quadruple therapy for eradication of Helicobacter pylori Full Text World Journal of Gastroenterology, February 21, 2013    Clinical Article

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Clinical Pearls in Gastroenterology

Highlights in Gastroenterology

What is the best strategy for CRC screening?

As published in the NEJM, researchers in the COLONPREV study (Spain) have reported that fecal immunochemical testing (FIT) is as effective as colonoscopy in the detection of colorectal cancer (CRC). The study population was 50-69 years of age and comprised of 26,703 subjects who underwent a one-time colonoscopy and 26,599 subjects who underwent FIT every 2 years. The primary outcome measure was CRC deaths at 10 years. Participation in screening was greater in the FIT group than the colonoscopy group (34.2% vs. 24.6%). Detection of CRC was similar between the two groups (0.1%). Advanced and non-advanced adenomas were detected more frequently in the colonoscopy group than the FIT group (1.9% vs. 0.9% [OR=2.3] and 4.2% vs. 0.4% [OR=9.8], respectively).

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PPIs increase risk of Clostridium difficile infection

Based on a meta-analysis involving 30 observational studies and 202,965 patients, proton pump inhibitor therapy has been shown to significantly increase the risk of infection with Clostridium difficile (OR = 2.15).

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Metformin improves survival in patients with DM and CRC

In a single institution study involving 424 patients with DM and CRC, those patients treated with metformin had a 30% improvement in OS compared with patients not treated with metformin. Specifically, the metformin-treated patients had a mean survival of 76.9 months compared to 56.9 months.

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Indexed Journals in Gastroenterology: Gastroenterology, American Journal of Gastroenterology, Gutmore

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