Gastroenterology - GI Oncology News & Articles

Available now at MDLinx Gastroenterology: Ranked summaries of the most clinically-relevant GI literature refreshed every 24 hours, as well as MDLinx Gastroenterology exclusive content

Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in your uniquely diverse field. In addition to general gastroenterology news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.
MDLinx Gastroenterology exclusive content includes: Monthly highlights of the "can't miss" articles chosen by our physician editor, D. Scott Cunningham, MD, PhD; clinical pearls from The Smartest Internist and Smartest Family Physician daily competitions, a collaboration from the editors of MDLinx and Cleveland Clinic Center for Continuing Education; and pearls from our Pediatrics Physician Review quizzes.

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Latest (26) Full Text Articles (318)

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

141 Modified technique of pancreaticogastrostomy for soft pancreas with two continuous hemstitch sutures: a single-center prospective study Journal of Gastrointestinal Surgery, June 12, 2013 Clinical Article

142 GSTM1 and GSTT1 polymorphism and susceptibility to esophageal cancer in high- and low-risk regions of India Tumor Biology, June 12, 2013 Clinical Article

143 EphA2 promotes epithelial–mesenchymal transition through the Wnt/β-catenin pathway in gastric cancer cells Oncogene, June 12, 2013 Review Article

144 Insulin receptor tyrosine kinase substrate activates EGFR/ERK signalling pathway and promotes cell proliferation of hepatocellular carcinoma Cancer Letters, June 12, 2013 Clinical Article

145 Costs of trastuzumab in combination with chemotherapy for HER2-positive advanced gastric or gastroesophageal junction cancer: does one Analysis fit all? Full Text Translational Gastrointestinal Cancer, June 11, 2013 Review Article

146 Computed tomographic colonography for colorectal cancer screening Cancer, June 11, 2013 Clinical Article

147 Mitomycin-c and capecitabine (MIXE) as salvage treatment in patients with refractory metastatic colorectal cancer: a retrospective study Anticancer Research, June 11, 2013 Clinical Article

148 Diagnostic and therapeutic role of endoscopy in gastroenteropancreatic neuroendocrine neoplasms Digestive and Liver Diseases, June 11, 2013 Review Article

149 Extra-intestinal malignancies in inflammatory bowel disease: Results of the 3rd ECCO Pathogenesis Scientific Workshop (III) Journal of Crohn's and Colitis, June 11, 2013 Clinical Article

150 A pilot study of salvage irinotecan monotherapy for advanced biliary tract cancer Anticancer Research, June 11, 2013 Clinical Article

151 Clinical significance of RECK promoter methylation in pancreatic ductal adenocarcinoma Tumor Biology, June 11, 2013 Clinical Article

152 Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer Full Text BMC Cancer, June 11, 2013 Clinical Article

153 A functional BRCA1 coding sequence genetic variant contributes to risk of esophageal squamous cell carcinoma Carcinogenesis, June 11, 2013 Clinical Article

154 Cloning and characterization of a novel human BRMS1 transcript variant in hepatocellular carcinoma cells Cancer Letters, June 11, 2013 Clinical Article

155 Mir-451 inhibits cell proliferation in human hepatocellular carcinoma through direct suppression of ikk-{beta} Carcinogenesis, June 11, 2013 Clinical Article

156 Extracellular DNA in pancreatic cancer promotes cell invasion and metastasis Cancer Research, June 11, 2013 Clinical Article

157 Laparoscopy-assisted vs. open total gastrectomy for advanced gastric cancer: long-term outcomes and technical aspects of a case-control study Journal of Gastrointestinal Surgery, June 11, 2013 Clinical Article

158 Deep hypothermia and low flow for surgery for abdominal or extraperitoneal tumors with cavoatrial extension Annals of Thoracic Surgery, June 11, 2013 Clinical Article

159 CT of gallbladder cancer and its mimics: a pattern-based approach Abdominal Imaging , June 11, 2013 Clinical Article

160 Combination of CYP inhibitor with MEK/ERK inhibitor enhances the inhibitory effect on ERK in BRAF mutant colon cancer cells Anticancer Research, June 11, 2013 Clinical Article

50 available pages First Previous 8 9 10 11 12 13 14 15 16 17 Next Last

Clinical Pearls in Gastroenterology

Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores: female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
33% of patients with suspected GERD are resistant or partially respond to PPIs
Infliximab is the only TNF inhibitor approved by the FDA for ulcerative colitis.

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Highlights in Gastroenterology

What is the best strategy for CRC screening?

As published in the NEJM, researchers in the COLONPREV study (Spain) have reported that fecal immunochemical testing (FIT) is as effective as colonoscopy in the detection of colorectal cancer (CRC). The study population was 50-69 years of age and comprised of 26,703 subjects who underwent a one-time colonoscopy and 26,599 subjects who underwent FIT every 2 years. The primary outcome measure was CRC deaths at 10 years. Participation in screening was greater in the FIT group than the colonoscopy group (34.2% vs. 24.6%). Detection of CRC was similar between the two groups (0.1%). Advanced and non-advanced adenomas were detected more frequently in the colonoscopy group than the FIT group (1.9% vs. 0.9% [OR=2.3] and 4.2% vs. 0.4% [OR=9.8], respectively).

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PPIs increase risk of Clostridium difficile infection

Based on a meta-analysis involving 30 observational studies and 202,965 patients, proton pump inhibitor therapy has been shown to significantly increase the risk of infection with Clostridium difficile (OR = 2.15).

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Metformin improves survival in patients with DM and CRC

In a single institution study involving 424 patients with DM and CRC, those patients treated with metformin had a 30% improvement in OS compared with patients not treated with metformin. Specifically, the metformin-treated patients had a mean survival of 76.9 months compared to 56.9 months.

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Most Popular Gastro Articles

Last month's top read Top Articles of 2012

1 Current opinion on optimal treatment for colorectal cancer Expert Review of Anticancer Therapy, May 13, 2013 Review Article

2 A survey of expert follow-up practices after successful endoscopic eradication therapy for Barretts esophagus with high-grade dysplasia and intramucosal adenocarcinoma Gastrointestinal Endoscopy, May 29, 2013

3 The impact of positive circumferential margin on survival following oesophagectomy using the new 7th TNM classification European Journal of Cardio-Thoracic Surgery, May 15, 2013

4 Risk Stratification of Hepatocellular Carcinoma in Hepatitis B e Antigen-Negative Carriers by Combining Viral Biomarkers The Journal of Infectious Diseases, May 10, 2013

5 Meta-analysis: the impact of oral anti-viral agents on the incidence of hepatocellular carcinoma in chronic hepatitis B Alimentary Pharmacology and Therapeutics, May 30, 2013 Evidence Based Medicine

6 Acid suppressive drugs and gastric cancer: A meta-analysis of observational studies World Journal of Gastroenterology, May 21, 2013 Free full text

7 Nonsteroidal anti-inflammatory drug use, chronic liver disease, and hepatocellular carcinoma Hepatology, May 23, 2013

8 United States-based practice patterns and resource utilization in advanced neuroendocrine tumor treatment World Journal of Gastroenterology, May 7, 2013 Free full text

9 Monoclonal antibodies in gastrointestinal cancers Expert Opinion on Biological Therapy, May 22, 2013 Review Article

10 Fibrolamellar variant of hepatocellular carcinoma does not have a better survival than conventional hepatocellular carcinoma - Results and treatment recommendations from the Childhood Liver Tumour Strategy Group (SIOPEL) experience European Journal of Cancer, May 24, 2013

11 The Increased Risk of Colon Cancer Due to Cigarette Smoking May Be Greater in Women than Men Cancer Epidemiology, Biomarkers & Prevention, May 3, 2013
Exclusive Author Commentary

12 Response to Chemotherapy in Metastatic Colorectal Cancer After Exposure to Oxaliplatin in the Adjuvant Setting Anticancer Research, April 9, 2013

13 High-dose FOLFIRI, Surgery, and Radiofrequency Ablation for Patients with Unresectable Liver Metastases from Colorectal Cancer Anticancer Research, April 9, 2013

14 Current status of screening for colorectal cancer Annals of Oncology, May 9, 2013 Review Article

15 Pancreatic neuroendocrine tumors: Clinical features, diagnosis and medical treatment: Advances Best Practice & Research Clinical Gastroenterology , April 29, 2013 Review Article

16 The effect of different dosing regimens of motesanib on the gallbladder: a randomized phase 1b study in patients with advanced solid tumors BMC Cancer, May 17, 2013 Free full text

17 Comparison of hepatocellular carcinoma (HCC), cholangiocarcinoma (CC), and combined HCC-CC (CHC) with each other based on microarray dataset Tumor Biology, May 24, 2013

18 Endoscopic Therapy for Barretts Esophagus and Early Esophageal Adenocarcinoma Gastroenterology Clinics of North America, April 2, 2013 Review Article

19 Risk of Cancer in Cases of Suspected Lynch Syndrome Without Germline Mutation Gastroenterology, April 23, 2013 Review Article

20 An analysis of the treatment effect of panitumumab on overall survival from a phase 3, randomized, controlled, multicenter trial (20020408) in patients with chemotherapy refractory metastatic colorectal cancer Targeted Oncology, April 29, 2013

Indexed Journals in Gastroenterology: Gastroenterology, American Journal of Gastroenterology, Gut more

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Gastroenterology - GI Oncology News & Articles

Articles

Clinical Pearls in Gastroenterology

Highlights in Gastroenterology

What is the best strategy for CRC screening?

PPIs increase risk of Clostridium difficile infection

Metformin improves survival in patients with DM and CRC

Most Popular Gastro Articles

Other Topics in Gastroenterology