Gastroenterology - GI Oncology News & Articles

Available now at MDLinx Gastroenterology: Ranked summaries of the most clinically-relevant GI literature refreshed every 24 hours, as well as MDLinx Gastroenterology exclusive content

Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in your uniquely diverse field. In addition to general gastroenterology news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.
MDLinx Gastroenterology exclusive content includes: Monthly highlights of the "can't miss" articles chosen by our physician editor, D. Scott Cunningham, MD, PhD; clinical pearls from The Smartest Internist and Smartest Family Physician daily competitions, a collaboration from the editors of MDLinx and Cleveland Clinic Center for Continuing Education; and pearls from our Pediatrics Physician Review quizzes.

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Latest (15) Full Text Articles (318)

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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61 Gd-EOB-DTPA-Enhanced MRI is Better than MDCT in Decision Making of Curative Treatment for Hepatocellular Carcinoma Annals of Surgical Oncology, May 15, 2013 Clinical Article

62 Long-term Outcomes Following Tumor Ablation for Treatment of Bilateral Colorectal Liver Metastases JAMA Surgery, May 15, 2013 Review Article

63 Feasibility of Sentinel Node Navigation Surgery after Non-curative Endoscopic Resection for Early Gastric Cancer Journal of Gastroenterology and Hepatology, May 15, 2013 Review Article

64 A Simple System to Predict Perihilar Cholangiocarcinoma Resectability Journal of Gastrointestinal Surgery, May 15, 2013 Review Article

65 Porcelain Gallbladder: A Benign Process or Concern for Malignancy? Journal of Gastrointestinal Surgery, May 15, 2013 Review Article

66 Combined use of AFP, CEA, CA125 and CAl9-9 improves the sensitivity for the diagnosis of gastric cancer Full Text BMC Gastroenterology, May 15, 2013 Review Article

67 Predicting Lymph Node Metastases in Early Esophageal Adenocarcinoma Using a Simple Scoring System Journal of the American College of Surgeons, May 15, 2013 Clinical Article

68 Expression of group IIA phospholipase A2 is an independent predictor of favorable outcome for patients with gastric cancer Human Pathology, May 15, 2013 Clinical Article

69 Gross pathological classification of peripheral cholangiocarcinoma determines the efficacy of hepatectomy Journal of Gastroenterology, May 15, 2013 Review Article

70 Decrease of 5-Hydroxymethylcytosine Is Associated with Progression of Hepatocellular Carcinoma through Downregulation of TET1 PLOS ONE, May 15, 2013 Evidence Based Medicine

71 Apigenin sensitizes doxorubicin-resistant hepatocellular carcinoma BEL-7402/ADM cells to doxorubicin via inhibiting PI3K/Akt/Nrf2 pathway Carcinogenesis, May 15, 2013 Clinical Article

72 A Pilot Study of Hepatic Arterial Infusion of Chemotherapy for Patients with Advanced Hepatocellular Carcinoma Who Have Failed Antiangiogenic Therapy Liver International, May 14, 2013 Review Article

73 Laparoscopy and peritoneal cytology: important prognostic tools to guide treatment selection in gastric adenocarcinoma ANZ Journal of Surgery, May 14, 2013 Clinical Article

74 Hepatocellular carcinoma in patients with chronic kidney disease Full Text World Journal of Gastroenterology, May 14, 2013 Review Article

75 Trans-arterial chemo-embolization is safe and effective for very elderly patients with hepatocellular carcinoma Full Text World Journal of Gastroenterology, May 14, 2013 Clinical Article

76 Regorafenib inhibits growth, angiogenesis and metastasis in a highly aggressive, orthotopic colon cancer model Molecular Cancer Therapeutics, May 14, 2013 Clinical Article

77 Correlation between response to chemotherapy with concomitant bevacizumab for hepatic metastasis of colorectal cancer and degree of enhancement using contrast-enhanced computed tomography Cancer Chemotherapy and Pharmacology, May 14, 2013 Clinical Article

78 The expression and role of Aquaporin 5 in esophageal squamous cell carcinoma Journal of Gastroenterology, May 14, 2013 Review Article

79 The oncogenic role of PTK7 in esophageal squamous cell carcinoma Cancer Science, May 14, 2013 Clinical Article

80 Multicenter Italian Experience in Liver Transplantation for Hepatocellular Carcinoma in HIV-Infected Patients Full Text The Oncologist, May 14, 2013 Clinical Article

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Clinical Pearls in Gastroenterology

Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores: female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
33% of patients with suspected GERD are resistant or partially respond to PPIs
Infliximab is the only TNF inhibitor approved by the FDA for ulcerative colitis.

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Gastroenterology

What is the best strategy for CRC screening?

As published in the NEJM, researchers in the COLONPREV study (Spain) have reported that fecal immunochemical testing (FIT) is as effective as colonoscopy in the detection of colorectal cancer (CRC). The study population was 50-69 years of age and comprised of 26,703 subjects who underwent a one-time colonoscopy and 26,599 subjects who underwent FIT every 2 years. The primary outcome measure was CRC deaths at 10 years. Participation in screening was greater in the FIT group than the colonoscopy group (34.2% vs. 24.6%). Detection of CRC was similar between the two groups (0.1%). Advanced and non-advanced adenomas were detected more frequently in the colonoscopy group than the FIT group (1.9% vs. 0.9% [OR=2.3] and 4.2% vs. 0.4% [OR=9.8], respectively).

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PPIs increase risk of Clostridium difficile infection

Based on a meta-analysis involving 30 observational studies and 202,965 patients, proton pump inhibitor therapy has been shown to significantly increase the risk of infection with Clostridium difficile (OR = 2.15).

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Metformin improves survival in patients with DM and CRC

In a single institution study involving 424 patients with DM and CRC, those patients treated with metformin had a 30% improvement in OS compared with patients not treated with metformin. Specifically, the metformin-treated patients had a mean survival of 76.9 months compared to 56.9 months.

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Most Popular Gastroenterology Articles

Last month's top read Top Articles of 2012

1 Endoscopic Therapy for Barretts Esophagus and Early Esophageal Adenocarcinoma Gastroenterology Clinics of North America, April 2, 2013 Review Article

2 High-dose FOLFIRI, Surgery, and Radiofrequency Ablation for Patients with Unresectable Liver Metastases from Colorectal Cancer Anticancer Research, April 9, 2013

3 Value of Highly Sensitive Fucosylated Fraction of Alpha-Fetoprotein for Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment Digestive Diseases and Sciences, April 18, 2013 Review Article

4 A risk for hepatocellular carcinoma still persists long-term after sustained virological response in patients with hepatitis C associated liver cirrhosis Clinical Infectious Diseases, April 26, 2013

5 Response to Chemotherapy in Metastatic Colorectal Cancer After Exposure to Oxaliplatin in the Adjuvant Setting Anticancer Research, April 9, 2013

6 Vitamin D and the Epidemiology of Upper Gastrointestinal Cancers: A Critical Analysis of the Current Evidence Cancer Epidemiology, Biomarkers & Prevention, April 8, 2013 Evidence Based Medicine

7 Chemopreventive and Therapeutic Potential of Tea Polyphenols in Hepatocellular Cancer Nutrition and Cancer, April 3, 2013 Review Article

8 Meat, fish, and esophageal cancer risk: a systematic review and dose-response meta-analysis Nutrition Reviews, April 15, 2013 Evidence Based Medicine Review Article

9 Improved Post-Transplant Survival in the United States for Patients with Cholangiocarcinoma After 2000 Digestive Diseases and Sciences, April 5, 2013

10 Oesophageal bacterial biofilm changes in gastro-oesophageal reflux disease, Barretts and oesophageal carcinoma: association or causality Alimentary Pharmacology and Therapeutics, April 29, 2013

11 Esophagogastric Metaplasia Relates to Nodal Metastases in Adenocarcinoma of Esophagus and Cardia Annals of Thoracic Surgery, April 9, 2013

12 Survival with up to 10-year Follow-up after Combination Therapy of Chemoembolization and Radiofrequency Ablation for the Treatment of Hepatocellular Carcinoma: Single-center Experience Journal of Vascular and Interventional Radiology, April 29, 2013

13 The corpus-predominant gastritis index may serve as an early marker of Helicobacter pylori-infected patients at risk of gastric cancer Alimentary Pharmacology and Therapeutics, April 18, 2013

14 Meta-analysis: preoperative transcatheter arterial chemoembolization does not improve prognosis of patients with resectable hepatocellular carcinoma BMC Gastroenterology, April 9, 2013 Free full text

15 A randomized phase II study of gemcitabine and S-1 combination therapy versus gemcitabine monotherapy for advanced biliary tract cancer Cancer Chemotherapy and Pharmacology, March 27, 2013

16 Impact of the number of resected lymph nodes on postoperative survival of patients with node-negative oesophageal squamous cell carcinoma European Journal of Cardio-Thoracic Surgery, March 22, 2013

17 A UGT1A1*28 and *6 genotype-directed phase I dose-escalation trial of irinotecan with fixed-dose capecitabine in Korean patients with metastatic colorectal cancer Cancer Chemotherapy and Pharmacology, April 18, 2013

18 Relationship Between Mesenteric Abnormalities on Computed Tomography and Malignancy: Clinical Findings and Outcomes of 359 Patients Journal of Clinical Gastroenterology, April 16, 2013

19 The Inpatient Economic and Mortality Impact of Hepatocellular Carcinoma from 2005 to 2009: Analysis of the U.S. Nationwide Inpatient Sample Liver International, April 22, 2013

20 Dietary intake of vegetables, folate, and antioxidants and the risk of Barretts esophagus Cancer Causes and Control, April 24, 2013

Indexed Journals in Gastroenterology: Gastroenterology, American Journal of Gastroenterology, Gut more

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Gastroenterology - GI Oncology News & Articles

Articles

Clinical Pearls in Gastroenterology

Highlights in Gastroenterology

What is the best strategy for CRC screening?

PPIs increase risk of Clostridium difficile infection

Metformin improves survival in patients with DM and CRC

Most Popular Gastroenterology Articles

Other Topics in Gastroenterology