Gastroenterology - Hepatology News & Articles

Available now at MDLinx Gastroenterology: Ranked summaries of the most clinically-relevant GI literature refreshed every 24 hours, as well as MDLinx Gastroenterology exclusive content

Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in your uniquely diverse field. In addition to general gastroenterology news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.
MDLinx Gastroenterology exclusive content includes: Monthly highlights of the "can't miss" articles chosen by our physician editor, D. Scott Cunningham, MD, PhD; clinical pearls from The Smartest Internist and Smartest Family Physician daily competitions, a collaboration from the editors of MDLinx and Cleveland Clinic Center for Continuing Education; and pearls from our Pediatrics Physician Review quizzes.

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Latest (19) Full Text Articles (440)

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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361 Acoustic radiation force impulse imaging--normal values of liver stiffness in healthy children Pediatric Radiology, April 25, 2013 Clinical Article

362 Liver SULmean at FDG PET/CT: Interreader Agreement and Impact of Placement of Volume of Interest Radiology, April 25, 2013 Clinical Article

363 Microbiota and Gut–Liver Axis: Their Influences on Obesity and Obesity-Related Liver Disease Journal of Pediatric Gastroenterology and Nutrition, April 25, 2013 Review Article

364 Evolution of fibrosis during HCV recurrence after liver transplantation - influence of IL-28B SNP and response to peg-IFN and ribavirin treatment Journal of Viral Hepatitis, April 25, 2013 Clinical Article

365 Non-selective betablocker therapy decreases intestinal permeability and serum levels of LBP and IL-6 in patients with cirrhosis Journal of Hepatology, April 25, 2013 Review Article

366 Impact of liver cysts in progression of polycystic kidney disease Central European Journal of Medicine, April 25, 2013 Clinical Article

367 Age-related Macular Degeneration and Modification of Systemic Complement Factor H Production Through Liver Transplantation Ophthalmology, April 25, 2013 Review Article

368 A patient who showed a pathologically complete response after undergoing treatment with XELOX plus bevacizumab for synchronous liver metastasis of grade H2 from sigmoid colon cancer Full Text Journal of Gastrointestinal Oncology, April 25, 2013

369 Incident Hepatitis C Virus Infection in Men Who Have Sex With Men: A Prospective Cohort Analysis, 1984-2011 Clinical Infectious Diseases, April 24, 2013 Clinical Article

370 Long-term effects of prophylactic and therapeutic lamivudine treatments in hepatitis B surface antigen-positive renal allograft recipients Clinical and Experimental Nephrology, April 24, 2013 Clinical Article

371 Liver Dysplasia: US Molecular Imaging with Targeted Contrast Agent Enables Early Assessment Radiology, April 24, 2013 Clinical Article

372 Differences in Metabolites of Different Tongue Coatings in Patients with Chronic Hepatitis B Full Text Evidence-based Complementary and Alternative Medicine , April 24, 2013 Clinical Article

373 Genetic Defects in Bile Acid Conjugation Cause Fat-Soluble Vitamin Deficiency Gastroenterology, April 24, 2013 Review Article

374 Dose adjustment in patients with liver cirrhosis: impact on adverse drug reactions and hospitalizations European Journal of Clinical Pharmacology, April 24, 2013 Clinical Article
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375 Response of liver metastases to preoperative radiochemotherapy in patients with locally advanced rectal cancer and resectable synchronous liver metastases Surgery, April 24, 2013 Clinical Article

376 C-reactive protein may be a prognostic factor in hepatocellular carcinoma with malignant portal vein invasion Full Text World Journal of Surgical Oncology, April 24, 2013 Clinical Article

377 Obliteration of Gastric Varices Improves the Arrival Time of Ultrasound Contrast Agents in Hepatic Artery and Vein Journal of Gastroenterology and Hepatology, April 24, 2013 Clinical Article

378 ACP5, a direct transcriptional target of FoxM1, promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma Oncogene, April 24, 2013 Clinical Article

379 Lipopolysaccharide blocks induction of unfolded protein response in human hepatoma cell lines Immunology Letters, April 24, 2013 Review Article

380 Functional status determines postoperative outcomes in elderly patients undergoing hepatic resections Journal of Surgical Oncology, April 24, 2013 Review Article

50 available pages First Previous 19 20 21 22 23 24 25 26 27 28 Next Last

Clinical Pearls in Gastroenterology

Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores: female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
33% of patients with suspected GERD are resistant or partially respond to PPIs
Infliximab is the only TNF inhibitor approved by the FDA for ulcerative colitis.

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Highlights in Gastroenterology

What is the best strategy for CRC screening?

As published in the NEJM, researchers in the COLONPREV study (Spain) have reported that fecal immunochemical testing (FIT) is as effective as colonoscopy in the detection of colorectal cancer (CRC). The study population was 50-69 years of age and comprised of 26,703 subjects who underwent a one-time colonoscopy and 26,599 subjects who underwent FIT every 2 years. The primary outcome measure was CRC deaths at 10 years. Participation in screening was greater in the FIT group than the colonoscopy group (34.2% vs. 24.6%). Detection of CRC was similar between the two groups (0.1%). Advanced and non-advanced adenomas were detected more frequently in the colonoscopy group than the FIT group (1.9% vs. 0.9% [OR=2.3] and 4.2% vs. 0.4% [OR=9.8], respectively).

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PPIs increase risk of Clostridium difficile infection

Based on a meta-analysis involving 30 observational studies and 202,965 patients, proton pump inhibitor therapy has been shown to significantly increase the risk of infection with Clostridium difficile (OR = 2.15).

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Metformin improves survival in patients with DM and CRC

In a single institution study involving 424 patients with DM and CRC, those patients treated with metformin had a 30% improvement in OS compared with patients not treated with metformin. Specifically, the metformin-treated patients had a mean survival of 76.9 months compared to 56.9 months.

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Most Popular Gastroenterology Articles

Last month's top read Top Articles of 2012

1 All-oral therapy with nucleotide inhibitors sofosbuvir and GS-0938 for 14 days in treatment-naive genotype 1 hepatitis C (NUCLEAR) Journal of Viral Hepatitis, April 2, 2013

2 Systematic review: pentoxifylline for the treatment of severe alcoholic hepatitis Alimentary Pharmacology and Therapeutics, April 3, 2013 Review Article

3 Telaprevir Versus Boceprevir in Chronic Hepatitis C: A Meta-Analysis of Data From Phase II and III Trials Clinical Therapeutics, March 5, 2013

4 Racial differences in nonalcoholic fatty liver disease in the U.S. population Obesity, March 29, 2013

5 Impact of oral silymarin on virus- and non-virus-specific T-cell responses in chronic hepatitis C infection Journal of Viral Hepatitis, April 16, 2013

6 Chronic HBV infection outside treatment guidelines: is treatment needed Antiviral Therapy , April 8, 2013

7 Statins are associated with a reduced risk of hepatocellular cancer: a systematic review and meta-analysis Gastroenterology, February 6, 2013 Evidence Based Medicine

8 Statins in Nonalcoholic Fatty Liver Disease and Steatohepatitis: Updated Review Current Atherosclerosis Reports, January 21, 2013 Review Article

9 Prevalence and causes of abnormal liver function in patients with celiac disease Liver International, April 15, 2013 Review Article

10 Incident hepatitis C virus infection in men who have sex with men: a prospective cohort analysis from 1984 to 2011 Clinical Infectious Diseases, April 4, 2013

11 Relationship of Non-alcoholic Fatty Liver Disease With Cholecystectomy in the US Population The American Journal of Gastroenterology, April 11, 2013

12 Prevalence, Risk Factors, and Impact of Isolated Antibody to Hepatitis B Core Antigen and Occult Hepatitis B Virus Infection in HIV-1-Infected Pregnant Women Clinical Infectious Diseases, April 11, 2013

13 Statin therapy improves response to interferon alfa and ribavirin in chronic hepatitis C: a systematic review and meta-analysis Antiviral Research , April 23, 2013 Evidence Based Medicine Review Article

14 Non-invasive serum fibrosis markers for screening and staging chronic hepatitis C virus (HCV) patients in a large U.S. cohort Clinical Infectious Diseases, April 18, 2013

15 Effect of Ritonavir-Boosted Danoprevir, a Potent Hepatitis C Virus Protease Inhibitor, on QTc Interval in Healthy Subjects: Results from a Thorough QT Study Drug Development Research, April 3, 2013

16 Role of hepatitis C virus substitutions and interleukin-28B polymorphism on response to peginterferon plus ribavirin in a prospective study of response-guided therapy Journal of Viral Hepatitis, April 9, 2013

17 Macrophage activation is a prognostic parameter for variceal bleeding and overall survival in patients with liver cirrhosis Journal of Hepatology, April 26, 2013 Review Article

18 Decreased Peripheral Blood CD4+/CD25+ Regulatory T Cells in Patients with Alcoholic Hepatitis Alcoholism: Clinical and Experimental Research, April 1, 2013

19 The Prevalence and Clinical Correlates of Nonalcoholic Fatty Liver Disease (NAFLD) in African Americans: The Multiethnic Study of Atherosclerosis (MESA) Digestive Diseases and Sciences, April 17, 2013

20 Hospital mortality over time in patients with specific complications of liver cirrhosis Liver International, March 7, 2013 Review Article

Indexed Journals in Gastroenterology: Gastroenterology, American Journal of Gastroenterology, Gut more

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Gastroenterology - Hepatology News & Articles

Articles

Clinical Pearls in Gastroenterology

Highlights in Gastroenterology

What is the best strategy for CRC screening?

PPIs increase risk of Clostridium difficile infection

Metformin improves survival in patients with DM and CRC

Most Popular Gastroenterology Articles

Other Topics in Gastroenterology