Gastroenterology - Hepatology News & Articles

Available now at MDLinx Gastroenterology: Ranked summaries of the most clinically-relevant GI literature refreshed every 24 hours, as well as MDLinx Gastroenterology exclusive content

Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in your uniquely diverse field. In addition to general gastroenterology news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.
MDLinx Gastroenterology exclusive content includes: Monthly highlights of the "can't miss" articles chosen by our physician editor, D. Scott Cunningham, MD, PhD; clinical pearls from The Smartest Internist and Smartest Family Physician daily competitions, a collaboration from the editors of MDLinx and Cleveland Clinic Center for Continuing Education; and pearls from our Pediatrics Physician Review quizzes.

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Latest (18) Full Text Articles (440)

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

261 Liver X receptor regulates arachidonic acid distribution and eicosanoid release in human macrophages Arteriosclerosis, Thrombosis, and Vascular Biology, May 28, 2013 Clinical Article

262 Liver abscesses after peritoneal venous shunt Full Text Case Reports in Gastroenterology, May 28, 2013

263 Autophagy enhances hepatocellular carcinoma progression by activation of mitochondrial β-oxidation Journal of Gastroenterology, May 28, 2013 Review Article

264 An intraductal papillary neoplasm of the bile duct mimicking a hemorrhagic hepatic cyst: a case report Full Text World Journal of Surgical Oncology, May 28, 2013

265 Low vitamin D serum concentration is associated with high levels of hepatitis B virus (HBV) replication in chronically infected patients Hepatology, May 24, 2013 Clinical Article

266 Clinical and histological determinants of nonalcoholic steatohepatitis and advanced fibrosis in elderly patients Hepatology, May 24, 2013 Clinical Article

267 Effect of lifetime alcohol consumption on the histologic severity of Non-Alcoholic Fatty Liver Disease Liver International, May 24, 2013 Clinical Article

268 Characterization of Hepatitis B virus genotypes and quantitative Hepatitis B surface antigen titres in North American tertiary referral liver centres Liver International, May 24, 2013 Clinical Article

269 Assessment of motivating factors associated with the initiation and completion of treatment for chronic hepatitis C virus (HCV) infection BMC Infectious Diseases, May 24, 2013 Review Article

270 Protein induced by vitamin k antagonist-ii (pivka-ii) is a reliable prognostic factor in small hepatocellular carcinoma World Journal of Surgery, May 24, 2013 Review Article

271 Fibrolamellar variant of hepatocellular carcinoma does not have a better survival than conventional hepatocellular carcinoma - Results and treatment recommendations from the Childhood Liver Tumour Strategy Group (SIOPEL) experience European Journal of Cancer, May 24, 2013 Clinical Article

272 The small molecule genistein increases hepcidin expression in human hepatocytes Hepatology, May 24, 2013 Review Article

273 Hepatic steatosis: quantification by proton density fat fraction with MR imaging versus liver biopsy Radiology, May 24, 2013 Review Article

274 Epigenetic regulation of miR-122 by PPARγ and hepatitis B virus X protein in hepatocellular carcinoma cells Hepatology, May 24, 2013 Review Article

275 Margin status remains an important determinant of survival after surgical resection of colorectal liver metastases in the era of modern chemotherapy Annals of Surgery, May 24, 2013 Clinical Article

276 Totally laparoscopic liver resections for primary and metastatic cancer in the elderly: safety, feasibility and short-term outcomes Surgical Endoscopy, May 24, 2013 Clinical Article

277 Hepatitis B virus vaccination in children with steroid sensitive nephrotic syndrome: Immunogenicity and safety? Vaccine , May 24, 2013 Review Article

278 Comparison of hepatocellular carcinoma (HCC), cholangiocarcinoma (CC), and combined HCC-CC (CHC) with each other based on microarray dataset Tumor Biology, May 24, 2013 Clinical Article

279 Overexpression of ARK5 is associated with poor prognosis in hepatocellular carcinoma Tumor Biology, May 24, 2013 Clinical Article

280 Rendezvous ductoplasty for biliary anastomotic stricture after living-donor liver transplantation Transplantation, May 24, 2013 Clinical Article

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Clinical Pearls in Gastroenterology

Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores: female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
33% of patients with suspected GERD are resistant or partially respond to PPIs
Infliximab is the only TNF inhibitor approved by the FDA for ulcerative colitis.

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Highlights in Gastroenterology

What is the best strategy for CRC screening?

As published in the NEJM, researchers in the COLONPREV study (Spain) have reported that fecal immunochemical testing (FIT) is as effective as colonoscopy in the detection of colorectal cancer (CRC). The study population was 50-69 years of age and comprised of 26,703 subjects who underwent a one-time colonoscopy and 26,599 subjects who underwent FIT every 2 years. The primary outcome measure was CRC deaths at 10 years. Participation in screening was greater in the FIT group than the colonoscopy group (34.2% vs. 24.6%). Detection of CRC was similar between the two groups (0.1%). Advanced and non-advanced adenomas were detected more frequently in the colonoscopy group than the FIT group (1.9% vs. 0.9% [OR=2.3] and 4.2% vs. 0.4% [OR=9.8], respectively).

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PPIs increase risk of Clostridium difficile infection

Based on a meta-analysis involving 30 observational studies and 202,965 patients, proton pump inhibitor therapy has been shown to significantly increase the risk of infection with Clostridium difficile (OR = 2.15).

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Metformin improves survival in patients with DM and CRC

In a single institution study involving 424 patients with DM and CRC, those patients treated with metformin had a 30% improvement in OS compared with patients not treated with metformin. Specifically, the metformin-treated patients had a mean survival of 76.9 months compared to 56.9 months.

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Gastroenterology - Hepatology News & Articles

Articles

Clinical Pearls in Gastroenterology

Highlights in Gastroenterology

What is the best strategy for CRC screening?

PPIs increase risk of Clostridium difficile infection

Metformin improves survival in patients with DM and CRC

Most Popular Gastro Articles

Other Topics in Gastroenterology