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1 Risk for coronary heart disease increases risk for colorectal neoplasm Clinical Gastroenterology and Hepatology , May 22, 2013 Clinical Article
2 Time trends in chemotherapy (administration and costs) and relative survival in stage III colon cancer patients a large population-based study from 1990 to 2008 Acta Oncologica, May 22, 2013 Clinical Guideline
3 Association of Nox1 and vinculin with colon cancer progression Cancer Investigation, May 22, 2013 Clinical Article
4 Excess mortality after curative surgery for colorectal cancer changes over time and differs for patients with colon versus rectal cancer Acta Oncologica, May 22, 2013 Clinical Article
5 Study protocol for "Moving Bright, Eating Smart" - a phase 2 clinical trial on the acceptability and feasibility of a diet and physical activity intervention to prevent recurrence in colorectal cancer survivors Full Text BMC Public Health, May 22, 2013 Review Article
6 Circulating micrornas as biomarkers of colorectal cancer: results from a genome-wide profiling and validation study Clinical Gastroenterology and Hepatology , May 22, 2013 Review Article
7 Neoadjuvant chemotherapy can improve outcome of colorectal cancer patients with unresectable metastasis International Journal of Colorectal Disease, May 22, 2013 Review Article
8 Anastomotic leakage as an outcome measure for quality of colorectal cancer surgery BMJ Quality & Safety, May 21, 2013 Review Article
9 Using Whole Disease Modeling to Inform Resource Allocation Decisions: Economic Evaluation of a Clinical Guideline for Colorectal Cancer Using a Single Model Value in Health, May 21, 2013 Clinical Guideline
10 Effects of Facilitated Team Meetings and Learning Collaboratives on Colorectal Cancer Screening Rates in Primary Care Practices: A Cluster Randomized Trial Full Text Annals of Family Medicine, May 21, 2013 Clinical Article
11 Stage at diagnosis and colorectal cancer survival in six high-income countries: A population-based study of patients diagnosed during 2000-2007 Acta Oncologica, May 21, 2013 Clinical Article
12 Phase II trial of temsirolimus alone and in combination with irinotecan for KRAS mutant metastatic colorectal cancer: Outcome and results of KRAS mutational analysis in plasma Acta Oncologica, May 21, 2013 Clinical Article
13 Identifying Molecular Targets of Lifestyle Modifications in Colon Cancer Prevention Frontiers in Oncology, May 21, 2013 Clinical Article
14 Comparison of treatment outcome in metastatic colorectal cancer patients included in a clinical trial versus daily practice in The Netherlands Acta Oncologica, May 21, 2013 Clinical Article
15 A modified supralevator pelvic exenteration for the treatment of locally advanced rectal cancer with vaginal and uterine invasion Surgery Today, May 21, 2013 Clinical Article
16 Local excision in early rectal cancer-outcome worse than expected: A population based study European Journal of Surgical Oncology, May 21, 2013 Clinical Article
17 CYP24A1 inhibition facilitates the anti-tumor effect of vitamin D3 on colorectal cancer cells Full Text World Journal of Gastroenterology, May 20, 2013 Clinical Article
18 Complicated postoperative recovery increases omission, delay and discontinuation of adjuvant chemotherapy in patients with colon cancer stage III Colorectal Disease, May 20, 2013 Clinical Article
19 Receipt of recommended surveillance among colorectal cancer survivors: a systematic review Journal of Cancer Survivorship, May 20, 2013 Evidence Based Medicine Review Article Clinical Guideline
20 Folic acid prevents the initial occurrence of sporadic colorectal adenoma in Chinese over 50 years of age: a randomized clinical trial Cancer Prevention Research, May 20, 2013 Clinical Article
As published in the NEJM, researchers in the COLONPREV study (Spain) have reported that fecal immunochemical testing (FIT) is as effective as colonoscopy in the detection of colorectal cancer (CRC). The study population was 50-69 years of age and comprised of 26,703 subjects who underwent a one-time colonoscopy and 26,599 subjects who underwent FIT every 2 years. The primary outcome measure was CRC deaths at 10 years. Participation in screening was greater in the FIT group than the colonoscopy group (34.2% vs. 24.6%). Detection of CRC was similar between the two groups (0.1%). Advanced and non-advanced adenomas were detected more frequently in the colonoscopy group than the FIT group (1.9% vs. 0.9% [OR=2.3] and 4.2% vs. 0.4% [OR=9.8], respectively).
Read the article summaryBased on a meta-analysis involving 30 observational studies and 202,965 patients, proton pump inhibitor therapy has been shown to significantly increase the risk of infection with Clostridium difficile (OR = 2.15).
Read the article summaryIn a single institution study involving 424 patients with DM and CRC, those patients treated with metformin had a 30% improvement in OS compared with patients not treated with metformin. Specifically, the metformin-treated patients had a mean survival of 76.9 months compared to 56.9 months.
Read the article summary1 Complications Following Colonoscopy With Anesthesia Assistance: A Population-Based Analysis JAMA Internal Medicine, March 18, 2013
2 Risk of Colorectal Cancer After Colonoscopy Compared With Flexible Sigmoidoscopy or No Lower Endoscopy Among Older Patients in the United States, 1998-2005 Mayo Clinic Proceedings, April 11, 2013
3 Prevalence of colorectal cancer and its precursor lesions in symptomatic and asymptomatic patients undergoing total colonoscopy: results of a large prospective, multicenter, controlled endoscopy study European Journal of Gastroenterology & Hepatology, April 19, 2013
4 A prospective study of the accuracy and concordance between in-situ and postfixation measurements of colorectal polyp size and their potential impact upon surveillance European Journal of Gastroenterology & Hepatology, April 18, 2013
5 Association Between Sex Hormones and Colorectal Cancer Risk in Men and Women Clinical Gastroenterology and Hepatology , April 5, 2013
6 Bisphosphonate Use and Risk of Colorectal Cancer: A Systematic Review and Meta-analysis British Journal of Clinical Pharmacology, April 22, 2013 Evidence Based Medicine Review Article
7 Trends in colorectal incidence by anatomic subsite from 1985 to 2005: a population-based study International Journal of Colorectal Disease, April 1, 2013 Review Article
8 Systematic Review and Quality Assessment of Cost-Effectiveness Analysis of Pharmaceutical Therapies for Advanced Colorectal Cancer Annals of Pharmacotherapy, April 8, 2013 Evidence Based Medicine Review Article
9 Associations Between Cigarette Smoking Status and Colon Cancer Prognosis Among Participants in North Central Cancer Treatment Group Phase III Trial N0147 Journal of Clinical Oncology, April 3, 2013
10 Polyps and Polypoid Lesions of the Colon International Journal of Surgical Pathology, April 2, 2013 Review Article
11 Long-term effectiveness of endoscopic screening on incidence and mortality of colorectal cancer: A randomized trial United European Gastroenterology Journal, April 9, 2013
12 Update on antiangiogenic therapy in colorectal cancer: aflibercept and regorafenib Journal of Gastrointestinal Oncology, April 25, 2013 Free full text
13 The role of faecal diversion in low rectal cancer: a review of 1791 patients having rectal resection with anastomosis for cancer, with and without a proximal stoma Colorectal Disease, April 23, 2013
14 Colorectal cancer risk factors in the detection of advanced adenoma and colorectal cancer Cancer Epidemiology, April 16, 2013
15 Multi-drug inhibition of the HER pathway in metastatic colorectal cancer: Results of a phase I study of pertuzumab plus cetuximab in cetuximab-refractory patients Investigational New Drugs, April 10, 2013
16 Magnetic Resonance Colonography for the Detection of Colorectal Neoplasia in Asymptomatic Adults Gastroenterology, April 10, 2013
17 Physician Recommendations and Patient Adherence After Inadequate Bowel Preparation on Screening Colonoscopy Digestive Diseases and Sciences, April 4, 2013
18 Combined Use of 18F-FDG PET/CT, DW-MRI, and DCE-MRI in Treatment Response for Preoperative Chemoradiation Therapy in Locally Invasive Rectal Cancers Clinical Nuclear Medicine , April 24, 2013
19 Involvement of previous non-participants cannot fully compensate for lower participation in a second round of FIT-screening Cancer Epidemiology, April 16, 2013
20 Harms of colonoscopy in a colorectal cancer screening programme with faecal occult blood test: A population-based cohort study Digestive and Liver Diseases, March 4, 2013
Indexed Journals in Gastroenterology: Gastroenterology, American Journal of Gastroenterology, Gut more
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