Gastroenterology - Colorectal Cancer/Polyps News & Articles

Available now at MDLinx Gastroenterology: Ranked summaries of the most clinically-relevant GI literature refreshed every 24 hours, as well as MDLinx Gastroenterology exclusive content

Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in your uniquely diverse field. In addition to general gastroenterology news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.
MDLinx Gastroenterology exclusive content includes: Monthly highlights of the "can't miss" articles chosen by our physician editor, D. Scott Cunningham, MD, PhD; clinical pearls from The Smartest Internist and Smartest Family Physician daily competitions, a collaboration from the editors of MDLinx and Cleveland Clinic Center for Continuing Education; and pearls from our Pediatrics Physician Review quizzes.

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Latest (9) Full Text Articles (290)

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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61 Colonic 15-PGDH Levels Are Stable Across Distance and Time and Are Not Perturbed by Aspirin Intervention Digestive Diseases and Sciences, May 10, 2013 Clinical Article

62 Using Pathway-Specific Comprehensive Exposure Scores in Epidemiology: Application to Oxidative Balance in a Pooled Case-Control Study of Incident, Sporadic Colorectal Adenomas American Journal of Epidemiology, May 10, 2013 Clinical Article

63 Tankyrase Inhibitor Suppresses Colorectal Tumor Growth Cancer Research, May 10, 2013 Clinical Article

64 Tumor-derived Tenascin-C Promotes the Epithelial-Mesenchymal Transition in Colorectal Cancer Cells Anticancer Research, May 10, 2013 Clinical Article

65 Laparoscopic Versus Open Multivisceral Resection for Primary Colorectal Cancer: Comparison of Perioperative Outcomes Journal of Gastrointestinal Surgery, May 10, 2013 Clinical Article

66 CCR4 mediates CCL17 (TARC)-induced migration of human colon cancer cells via RhoA/Rho-kinase signaling International Journal of Colorectal Disease, May 10, 2013 Review Article

67 Mutation-specific antibody detects mutant BRAF^V600E protein expression in human colon carcinomas Cancer, May 10, 2013 Review Article

68 Adenoma, advanced adenoma and colorectal cancer prevalence in asymptomatic 40 to 49-year-olds with a first-degree family history of colorectal cancer Colorectal Disease, May 9, 2013 Clinical Article

69 Current status of screening for colorectal cancer Annals of Oncology, May 9, 2013 Review Article Clinical Article

70 Phase I trial of the combination of the Akt inhibitor nelfinavir and chemoradiation for locally advanced rectal cancer Radiotherapy & Oncology, May 9, 2013 Clinical Article

71 Myofibroblast activation in colorectal cancer lymph node metastases British Journal of Cancer, May 9, 2013 Clinical Article

72 Population-Based Use of Sphincter-Preserving Surgery in Patients With Rectal Cancer: Is There Room for Improvement Diseases of the Colon and Rectum, May 9, 2013 Clinical Article

73 Chronic inhibition of tumor cell-derived VEGF enhances the malignant phenotype of colorectal cancer cells Full Text BMC Cancer, May 9, 2013 Clinical Article

74 Hostmicrobiota interaction and intestinal stem cells in chronic inflammation and colorectal cancer Expert Review of Clinical Immunology, May 9, 2013 Clinical Article

75 Monitoring of Circulating Tumor Cells in Patients Undergoing Surgery for Hepatic Metastases from Colorectal Cancer Anticancer Research, May 9, 2013 Clinical Article

76 Changes in CO2 Concentration Increase the Invasive Ability of Colon Cancer Cells Anticancer Research, May 9, 2013 Clinical Article

77 Reduced succinate dehydrogenase B expression is associated with growth and de-differentiation of colorectal cancer cells Tumor Biology, May 9, 2013 Clinical Article

78 Cullin 4B is a novel prognostic marker that correlates with colon cancer progression and pathogenesis Medical Oncology, May 9, 2013 Clinical Article

79 Postoperative peripheral blood monocyte count correlates with postoperative bile leakage in patients with colorectal liver metastases after hepatic resection Langenbeck's Archives of Surgery, May 8, 2013 Clinical Article

80 Transarterial Chemoembolization Using DEBIRI for Treatment of Hepatic Metastases from Colorectal Cancer Anticancer Research, May 8, 2013 Clinical Article

50 available pages First Previous 4 5 6 7 8 9 10 11 12 13 Next Last

Clinical Pearls in Gastroenterology

Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores: female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
33% of patients with suspected GERD are resistant or partially respond to PPIs
Infliximab is the only TNF inhibitor approved by the FDA for ulcerative colitis.

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Gastroenterology

What is the best strategy for CRC screening?

As published in the NEJM, researchers in the COLONPREV study (Spain) have reported that fecal immunochemical testing (FIT) is as effective as colonoscopy in the detection of colorectal cancer (CRC). The study population was 50-69 years of age and comprised of 26,703 subjects who underwent a one-time colonoscopy and 26,599 subjects who underwent FIT every 2 years. The primary outcome measure was CRC deaths at 10 years. Participation in screening was greater in the FIT group than the colonoscopy group (34.2% vs. 24.6%). Detection of CRC was similar between the two groups (0.1%). Advanced and non-advanced adenomas were detected more frequently in the colonoscopy group than the FIT group (1.9% vs. 0.9% [OR=2.3] and 4.2% vs. 0.4% [OR=9.8], respectively).

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PPIs increase risk of Clostridium difficile infection

Based on a meta-analysis involving 30 observational studies and 202,965 patients, proton pump inhibitor therapy has been shown to significantly increase the risk of infection with Clostridium difficile (OR = 2.15).

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Metformin improves survival in patients with DM and CRC

In a single institution study involving 424 patients with DM and CRC, those patients treated with metformin had a 30% improvement in OS compared with patients not treated with metformin. Specifically, the metformin-treated patients had a mean survival of 76.9 months compared to 56.9 months.

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Most Popular Gastroenterology Articles

Last month's top read Top Articles of 2012

1 Complications Following Colonoscopy With Anesthesia Assistance: A Population-Based Analysis JAMA Internal Medicine, March 18, 2013

2 Risk of Colorectal Cancer After Colonoscopy Compared With Flexible Sigmoidoscopy or No Lower Endoscopy Among Older Patients in the United States, 1998-2005 Mayo Clinic Proceedings, April 11, 2013

3 Prevalence of colorectal cancer and its precursor lesions in symptomatic and asymptomatic patients undergoing total colonoscopy: results of a large prospective, multicenter, controlled endoscopy study European Journal of Gastroenterology & Hepatology, April 19, 2013

4 A prospective study of the accuracy and concordance between in-situ and postfixation measurements of colorectal polyp size and their potential impact upon surveillance European Journal of Gastroenterology & Hepatology, April 18, 2013

5 Association Between Sex Hormones and Colorectal Cancer Risk in Men and Women Clinical Gastroenterology and Hepatology , April 5, 2013

6 Bisphosphonate Use and Risk of Colorectal Cancer: A Systematic Review and Meta-analysis British Journal of Clinical Pharmacology, April 22, 2013 Evidence Based Medicine Review Article

7 Trends in colorectal incidence by anatomic subsite from 1985 to 2005: a population-based study International Journal of Colorectal Disease, April 1, 2013 Review Article

8 Systematic Review and Quality Assessment of Cost-Effectiveness Analysis of Pharmaceutical Therapies for Advanced Colorectal Cancer Annals of Pharmacotherapy, April 8, 2013 Evidence Based Medicine Review Article

9 Associations Between Cigarette Smoking Status and Colon Cancer Prognosis Among Participants in North Central Cancer Treatment Group Phase III Trial N0147 Journal of Clinical Oncology, April 3, 2013

10 Polyps and Polypoid Lesions of the Colon International Journal of Surgical Pathology, April 2, 2013 Review Article

11 Long-term effectiveness of endoscopic screening on incidence and mortality of colorectal cancer: A randomized trial United European Gastroenterology Journal, April 9, 2013

12 Update on antiangiogenic therapy in colorectal cancer: aflibercept and regorafenib Journal of Gastrointestinal Oncology, April 25, 2013 Free full text

13 The role of faecal diversion in low rectal cancer: a review of 1791 patients having rectal resection with anastomosis for cancer, with and without a proximal stoma Colorectal Disease, April 23, 2013

14 Colorectal cancer risk factors in the detection of advanced adenoma and colorectal cancer Cancer Epidemiology, April 16, 2013

15 Multi-drug inhibition of the HER pathway in metastatic colorectal cancer: Results of a phase I study of pertuzumab plus cetuximab in cetuximab-refractory patients Investigational New Drugs, April 10, 2013

16 Magnetic Resonance Colonography for the Detection of Colorectal Neoplasia in Asymptomatic Adults Gastroenterology, April 10, 2013

17 Physician Recommendations and Patient Adherence After Inadequate Bowel Preparation on Screening Colonoscopy Digestive Diseases and Sciences, April 4, 2013

18 Combined Use of 18F-FDG PET/CT, DW-MRI, and DCE-MRI in Treatment Response for Preoperative Chemoradiation Therapy in Locally Invasive Rectal Cancers Clinical Nuclear Medicine , April 24, 2013

19 Involvement of previous non-participants cannot fully compensate for lower participation in a second round of FIT-screening Cancer Epidemiology, April 16, 2013

20 Harms of colonoscopy in a colorectal cancer screening programme with faecal occult blood test: A population-based cohort study Digestive and Liver Diseases, March 4, 2013

Indexed Journals in Gastroenterology: Gastroenterology, American Journal of Gastroenterology, Gut more

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Gastroenterology - Colorectal Cancer/Polyps News & Articles

Articles

Clinical Pearls in Gastroenterology

Highlights in Gastroenterology

What is the best strategy for CRC screening?

PPIs increase risk of Clostridium difficile infection

Metformin improves survival in patients with DM and CRC

Most Popular Gastroenterology Articles

Other Topics in Gastroenterology