Available now at MDLinx Gastroenterology: Ranked summaries of the most clinically-relevant GI literature refreshed every 24 hours, as well as MDLinx Gastroenterology exclusive content
Your Unread Messages in Gastroenterology
See All >> Messages include industry-sponsored communications and special communications from MDLinx
Patients 50+ may be at increased risk for pneumococcal disease. Learn what you can do.
Smartest Doc Challenge
MDLinx
Pediatric Gastroenterology Clinical Pearls
D Scott Cunningham MD, PhD
Site Editor, MDLinx
Transition rates for adenomas to CRC
Jill Baker
MDLinx Career Center
New Jobs in Your Specialty
MDLinx Top Read
MDLinx
Are your journals collecting cobwebs?
MDLinx Conference Center
MDLinx
June Conference Calendar
441 Risk of Colorectal Cancer After Colonoscopy Compared With Flexible Sigmoidoscopy or No Lower Endoscopy Among Older Patients in the United States, 1998-2005 Mayo Clinic Proceedings, April 11, 2013 Clinical Article
442 The role of number of meals, coffee intake, salt and type of cookware on colorectal cancer development in the context of the Mediterranean diet Public Health Nutrition, April 11, 2013 Clinical Article
443 Three-dimensional whole-liver perfusion magnetic resonance imaging in patients with hepatocellular carcinomas and colorectal hepatic metastases Full Text BMC Gastroenterology, April 11, 2013 Clinical Article
444 A real-life experience using panitumumab in chemo-refractory metastatic colorectal cancer patients: a retrospective analysis at the Jewish General Hospital, 2009-2012 Full Text Current Oncology, April 11, 2013 Clinical Article
445 Epidural vs. intravenous fentanyl during colorectal surgery using a double-blind, double-dummy design Acta Anaesthesiologica Scandinavica, April 11, 2013 Clinical Article
446 Validation of Self-Reported Colorectal Cancer Screening Behaviors Among Appalachian Residents Public Health Nursing, April 11, 2013 Clinical Article
447 Second primary colorectal cancer in the era of prevalent screening and imaging ANZ Journal of Surgery, April 11, 2013 Review Article
448 Surgery in asymptomatic patients with colorectal cancer and unresectable liver metastases: the authors' experience Full Text OncoTargets and Therapy, April 11, 2013 Clinical Article
449 A pilot study of natural orifice transanal endoscopic total mesorectal excision with laparoscopic assistance for rectal cancer Surgical Endoscopy, April 11, 2013 Clinical Article
450 Comparison of Endoscopic Resection Therapies for Rectal Carcinoid Tumor: Endoscopic Submucosal Dissection Versus Endoscopic Mucosal Resection Using Band Ligation Journal of Clinical Gastroenterology, April 11, 2013 Clinical Article
451 Cytotoxic Activity of Kenaf Seed Oils from Supercritical Carbon Dioxide Fluid Extraction towards Human Colorectal Cancer (HT29) Cell Lines Full Text Evidence-based Complementary and Alternative Medicine , April 11, 2013 Clinical Article
452 Expression of ZNF148 in different developing stages of colorectal cancer and its prognostic value Cancer, April 11, 2013 Clinical Article
453 Psychological Correlates of Sexual Dysfunction in Female Rectal and Anal Cancer Survivors: Analysis of Baseline Intervention Data The Journal of Sexual Medicine, April 11, 2013 Clinical Article
454 Laparoscopic Extralevator Abdominoperineal Resection for Rectal Carcinoma with Transabdominal Levator Transection Annals of Surgical Oncology, April 11, 2013 Clinical Article
455 Concomitant BRAF and PI3K/mTOR Blockade is Required for Effective Treatment of BRAFV600E Colorectal Cancer Clinical Cancer Research, April 11, 2013 Clinical Article
456 Parallel overexpression and clinical significance of kallikrein-related peptidases 7 and 14 (KLK7KLK14) in colon cancer Thrombosis and Haemostasis, April 11, 2013 Clinical Article
457 Non-nuclear localization of Ki-67 in human colorectal cancer cells grown as multicellular layers Full Text Archives of Pharmacal Research, April 11, 2013 Clinical Article
458 Multi-drug inhibition of the HER pathway in metastatic colorectal cancer: Results of a phase I study of pertuzumab plus cetuximab in cetuximab-refractory patients Investigational New Drugs, April 10, 2013 Clinical Article
459 Multicenter phase II study of modified FOLFOX6 as neoadjuvant chemotherapy for patients with unresectable liver-only metastases from colorectal cancer in Japan: ROOF study International Journal of Clinical Oncology, April 10, 2013 Clinical Article
460 Chemoprevention of Colorectal Neoplasia in Inflammatory Bowel Disease Inflammation & Allergy - Drug Targets, April 10, 2013 Clinical Article
As published in the NEJM, researchers in the COLONPREV study (Spain) have reported that fecal immunochemical testing (FIT) is as effective as colonoscopy in the detection of colorectal cancer (CRC). The study population was 50-69 years of age and comprised of 26,703 subjects who underwent a one-time colonoscopy and 26,599 subjects who underwent FIT every 2 years. The primary outcome measure was CRC deaths at 10 years. Participation in screening was greater in the FIT group than the colonoscopy group (34.2% vs. 24.6%). Detection of CRC was similar between the two groups (0.1%). Advanced and non-advanced adenomas were detected more frequently in the colonoscopy group than the FIT group (1.9% vs. 0.9% [OR=2.3] and 4.2% vs. 0.4% [OR=9.8], respectively).
Read the article summaryBased on a meta-analysis involving 30 observational studies and 202,965 patients, proton pump inhibitor therapy has been shown to significantly increase the risk of infection with Clostridium difficile (OR = 2.15).
Read the article summaryIn a single institution study involving 424 patients with DM and CRC, those patients treated with metformin had a 30% improvement in OS compared with patients not treated with metformin. Specifically, the metformin-treated patients had a mean survival of 76.9 months compared to 56.9 months.
Read the article summary1 The impact of fair colonoscopy preparation on colonoscopy use and adenoma miss rates in patients undergoing outpatient colonoscopy Gastrointestinal Endoscopy, May 6, 2013
2 Adenoma, advanced adenoma and colorectal cancer prevalence in asymptomatic 40 to 49-year-olds with a first-degree family history of colorectal cancer Colorectal Disease, May 9, 2013
3 Identifying Molecular Targets of Lifestyle Modifications in Colon Cancer Prevention Frontiers in Oncology, May 21, 2013
4 Association between Helicobacter pylori infection and the risk of colorectal neoplasia: a systematic review and meta-analysis Colorectal Disease, May 16, 2013 Evidence Based Medicine Review Article
5 Regorafenib inhibits growth, angiogenesis and metastasis in a highly aggressive, orthotopic colon cancer model Molecular Cancer Therapeutics, May 14, 2013
6 Relationship of colonoscopy-detected serrated polyps with synchronous advanced neoplasia in average-risk individuals Gastrointestinal Endoscopy, May 1, 2013
7 False negative fecal occult blood test may be associated with increased mortality from colorectal cancer Digestive Diseases and Sciences, May 23, 2013
8 Human papillomavirus infection and colorectal cancer risk: a meta-analysis Colorectal Disease, May 3, 2013
9 More Comprehensive Discussion of CRC Screening Associated With Higher Screening The American Journal of Managed Care, May 6, 2013 Free full text Review Article
10 Complications Following Colonoscopy With Anesthesia Assistance: A Population-Based Analysis JAMA Internal Medicine, March 18, 2013
11 Predictors of Colorectal Cancer Screening Variation Among Primary-Care Providers and Clinics The American Journal of Gastroenterology, May 15, 2013 Review Article
12 Natural history of colorectal adenomas: Birth cohort analysis among 3.6 million participants of screening colonoscopy Cancer Epidemiology, Biomarkers & Prevention, May 3, 2013
13 Improving Hepatocellular Carcinoma Screening: Applying Lessons From Colorectal Cancer Screening Clinical Gastroenterology and Hepatology , May 7, 2013
14 Current status of screening for colorectal cancer Annals of Oncology, May 9, 2013 Review Article
15 Strategies for expanding colorectal cancer screening at community health centers CA: A Cancer Journal for Clinicians, May 20, 2013 Free full text
16 Anastomotic leakage as an outcome measure for quality of colorectal cancer surgery BMJ Quality & Safety, May 21, 2013 Review Article
17 Receipt of recommended surveillance among colorectal cancer survivors: a systematic review Journal of Cancer Survivorship, May 20, 2013 Evidence Based Medicine Review Article Clinical Guideline
18 Design of a randomized controlled trial to assess the comparative effectiveness of a multifaceted intervention to improve adherence to colorectal cancer screening among patients cared for in a community health center BMC Health Services Research, May 15, 2013 Free full text Review Article
19 Tracking the Molecular Features of Nonpolypoid Colorectal Neoplasms: A Systematic Review and Meta-Analysis The American Journal of Gastroenterology, May 10, 2013
20 Can selenium levels act as a marker of colorectal cancer risk BMC Cancer, April 30, 2013 Free full text
Indexed Journals in Gastroenterology: Gastroenterology, American Journal of Gastroenterology, Gut more
Register now to view all the MDLinx contents (FREE)!
Login
Stay current - Media Tool
♦ Subscribe to our free RSS feeds:
Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More ♦
♦ Follow Us on Twitter
Twitter is a rich source of instantly updated information. Join today and follow @MDLinx to start receiving tweets. Learn More ♦
Close